期刊
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
卷 42, 期 3, 页码 454-470出版社
SAGE PUBLICATIONS INC
DOI: 10.1177/0271678X211033732
关键词
Cerebral autoregulation; near-infrared spectroscopy; neuroimaging; transcranial Doppler ultrasound; stroke
This article discusses the importance of reperfusion treatment in acute ischemic stroke patients and highlights the impact of blood pressure on cerebral perfusion. It emphasizes the importance of effective blood pressure management in the early stages of stroke, and suggests that bedside monitoring of cerebral perfusion and oxygenation can help guide treatment and improve outcomes.
Restoring perfusion to ischemic tissue is the primary goal of acute ischemic stroke care, yet only a small portion of patients receive reperfusion treatment. Since blood pressure (BP) is an important determinant of cerebral perfusion, effective BP management could facilitate reperfusion. But how BP should be managed in very early phase of ischemic stroke remains a contentious issue, due to the lack of clear evidence. Given the complex relationship between BP and cerebral blood flow (CBF)-termed cerebral autoregulation (CA)-bedside monitoring of cerebral perfusion and oxygenation could help guide BP management, thereby improve stroke patient outcome. The aim of INFOMATAS is to 'identify novel therapeutic targets for treatment and management in acute ischemic stroke'. In this review, we identify novel physiological parameters which could be used to guide BP management in acute stroke, and explore methodologies for monitoring them at the bedside. We outline the challenges in translating these potential prognostic markers into clinical use.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据