4.7 Review

Emerging roles of angiopoietin-like proteins in inflammation: Mechanisms and potential as pharmacological targets

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Orthopedics

ANGPTL2 Promotes Inflammation via Integrin α5β1 in Chondrocytes

Mami Takano et al.

Summary: The study suggests that ANGPTL2 may induce the expression of inflammatory factors in chondrocytes by activating the integrin α5β1/MAPKs, Akt, and NF-κB signaling pathway.

CARTILAGE (2021)

Article Cell Biology

ANGPTL2 Induces Synovial Inflammation via LILRB2

Sayuri Nishiyama et al.

Summary: This study elucidates the mechanism by which ANGPTL2 induces inflammation via LILRB2 in synovial cells, with the finding that an anti-LILRB2 antibody can decrease the expression of inflammatory factors, offering a potential new avenue for treating osteoarthritis.

INFLAMMATION (2021)

News Item Biotechnology & Applied Microbiology

FDA approves first anti-ANGPTL3 antibody, for rare cardiovascular indication

Asher Mullard

NATURE REVIEWS DRUG DISCOVERY (2021)

Article Clinical Neurology

Angiopoietin-like protein 4 and clinical outcomes in ischemic stroke patients

Xiaowei Zheng et al.

Summary: Higher plasma ANGPTL-4 concentration was associated with poor prognosis in acute ischemic stroke patients, suggesting that ANGPTL-4 might be a prognostic marker for ischemic stroke.

ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2021)

Article Endocrinology & Metabolism

Angiopoietin-like 8 Improves Insulin Resistance and Attenuates Adipose Tissue Inflammation in Diet-Induced Obese Mice

Deng Luo et al.

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES (2020)

Article Engineering, Biomedical

Dual functional nanoparticles containing SOX duo and ANGPT4 shRNA for osteoarthritis treatment

Se-Young Jeong et al.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS (2020)

Review Biochemistry & Molecular Biology

Structure and Function of Angiopoietin-like Protein 3 (ANGPTL3) in Atherosclerosis

Xinjie Lu

CURRENT MEDICINAL CHEMISTRY (2020)

Article Biochemistry & Molecular Biology

Histone methyltransferase G9a protects against acute liver injury through GSTP1

Yu Zhang et al.

CELL DEATH AND DIFFERENTIATION (2020)

Article Medicine, Research & Experimental

Antibodies to watch in 2020

Helene Kaplon et al.

Review Biochemistry & Molecular Biology

Chapter 22: Structural and signaling functions of integrins

Yasmin A. Kadry et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2020)

Article Medicine, General & Internal

Evinacumab for Homozygous Familial Hypercholesterolemia

Frederick J. Raal et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Article Medicine, General & Internal

Evinacumab in Patients with Refractory Hypercholesterolemia

Robert S. Rosenson et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Article Biochemistry & Molecular Biology

Intestinal vitamin D receptor modulates lipid metabolism, adipose tissue inflammation and liver steatosis in obese mice

Daniel Jahn et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2019)

Review Cardiac & Cardiovascular Systems

Inflammation and its resolution in atherosclerosis: mediators and therapeutic opportunities

Magnus Back et al.

NATURE REVIEWS CARDIOLOGY (2019)

Article Immunology

Angiopoietin-like proteins in multiple sclerosis

Rabeah Al-Temaimi et al.

JOURNAL OF NEUROIMMUNOLOGY (2019)

Article Endocrinology & Metabolism

Angiopoietin-like 2 upregulation promotes human chondrocyte injury via NF-κB and p38/MAPK signaling pathway

Wenshan Shan et al.

JOURNAL OF BONE AND MINERAL METABOLISM (2019)

Article Biochemistry & Molecular Biology

ANGPTL3 inhibits renal cell carcinoma metastasis by inhibiting VASP phosphorylation

Tangliang Zhao et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2019)

Article Multidisciplinary Sciences

Angptl8 mediates food-driven resetting of hepatic circadian clock in mice

Siyu Chen et al.

NATURE COMMUNICATIONS (2019)

Article Medicine, Research & Experimental

Antiinflammatory activity of ANGPTL4 facilitates macrophage polarization to induce cardiac repair

Dong Im Cho et al.

JCI INSIGHT (2019)

Article Biochemistry & Molecular Biology

Angptl2 deficiency attenuates paraquat (PQ)-induced lung injury in mice by altering inflammation, oxidative stress and fibrosis through NF-κB pathway

Wei Yang et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)

Letter Cardiac & Cardiovascular Systems

Reduced Blood Lipid Levels With In Vivo CRISPR-Cas9 Base Editing of ANGPTL3

Alexandra C. Chadwick et al.

CIRCULATION (2018)

Review Biochemistry & Molecular Biology

Angiopoietin-Like Proteins in Angiogenesis, Inflammation and Cancer

Carmine Carbone et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Article Pharmacology & Pharmacy

Kaempferol modulates Angiopoietin-like protein 2 expression to lessen the mastitis in mice

Hong-Bo Xiao et al.

PHARMACOLOGICAL REPORTS (2018)

Article Multidisciplinary Sciences

Structures of Angptl3 and Angptl4, modulators of triglyceride levels and coronary artery disease

Ekaterina Biterova et al.

SCIENTIFIC REPORTS (2018)

Article Ophthalmology

Fenofibrate Exerts Protective Effects in Diabetic Retinopathy via Inhibition of the ANGPTL3 Pathway

Na Wang et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2018)

Review Cardiac & Cardiovascular Systems

Angiopoietin-Like 3 (ANGPTL3) and Atherosclerosis: Lipid and Non-Lipid Related Effects

Maria Giovanna Lupo et al.

JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE (2018)

Review Medicine, Research & Experimental

Angiopoietin-Tie signalling in the cardiovascular and lymphatic systems

Lauri Eklund et al.

CLINICAL SCIENCE (2017)

Article Urology & Nephrology

ELABELA and an ELABELA Fragment Protect against AKI

Hong Chen et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2017)

Review Endocrinology & Metabolism

Angiopoietin-like 3 in lipoprotein metabolism

Sander Kersten

NATURE REVIEWS ENDOCRINOLOGY (2017)

Letter Medicine, General & Internal

ANGPTL3 Inhibition in Homozygous Familial Hypercholesterolemia

Daniel Gaudet et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Medicine, General & Internal

Cardiovascular and Metabolic Effects of ANGPTL3 Antisense Oligonucleotides

Mark J. Graham et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Medicine, General & Internal

Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease

F. E. Dewey et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Review Cell Biology

High Circulating Levels of ANGPTL2: Beyond a Clinical Marker of Systemic Inflammation

Nathalie Thorin-Trescases et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2017)

Review Medicine, Research & Experimental

Potential Role of ANGPTL4 in the Cross Talk between Metabolism and Cancer through PPAR Signaling Pathway

Laura La Paglia et al.

PPAR RESEARCH (2017)

Article Endocrinology & Metabolism

ANGPTL8 promotes the ability of ANGPTL3 to bind and inhibit lipoprotein lipase

Xun Chi et al.

MOLECULAR METABOLISM (2017)

Article Cell Biology

Knockdown of Angiopoietin-Like Protein 2 Ameliorates Diabetic Nephropathy by Inhibiting TLR4

Suxia Yang et al.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2017)

Article Immunology

A guiding map for inflammation

Mihai G. Netea et al.

NATURE IMMUNOLOGY (2017)

Article Biochemistry & Molecular Biology

Angiopoietin-like protein 3 and 4 expression 4 and their serum levels in hepatocellular carcinoma

Amal S. El-Shal et al.

CYTOKINE (2017)

Article Evolutionary Biology

Evolution of the angiopoietin-like gene family in teleosts and their role in skin regeneration

Rita A. Costa et al.

BMC EVOLUTIONARY BIOLOGY (2017)

Review Pathology

Nonalcoholic Fatty Liver Disease: Pathogenesis and Disease Spectrum

Timothy Hardy et al.

ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 11 (2016)

Article Biochemistry & Molecular Biology

MicroRNA-134 actives lipoprotein lipase-mediated lipid accumulation and inflammatory response by targeting angiopoietin-like 4 in THP-1 macrophages

Gang Lan et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2016)

Article Cardiac & Cardiovascular Systems

Circulating angiopoietin-like protein 8 (betatrophin) association with HsCRP and metabolic syndrome

Mohamed Abu-Farha et al.

CARDIOVASCULAR DIABETOLOGY (2016)

Article Biology

Structural characterization of ANGPTL8 (betatrophin) with its interacting partner lipoprotein lipase

Amnah Siddiqa et al.

COMPUTATIONAL BIOLOGY AND CHEMISTRY (2016)

Article Medicine, General & Internal

Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease

Frederick F. Dewey et al.

NEW ENGLAND JOURNAL OF MEDICINE (2016)

Article Multidisciplinary Sciences

ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression

Binod Aryal et al.

NATURE COMMUNICATIONS (2016)

Review Biochemistry & Molecular Biology

The ANGPTL3-4-8 model, a molecular mechanism for triglyceride trafficking

Ren Zhang

OPEN BIOLOGY (2016)

Article Multidisciplinary Sciences

Upregulation of ANGPTL6 in mouse keratinocytes enhances susceptibility to psoriasis

Hiroki Tanigawa et al.

SCIENTIFIC REPORTS (2016)

Article Biochemistry & Molecular Biology

Angiopoietin-like protein 2 induces proinflammatory responses in peritoneal cells

Masato Umikawa et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)

Article Infectious Diseases

Host biomarkers are associated with progression to dengue haemorrhagic fever: a nested case-control study

Andrea L. Conroy et al.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2015)

Article Gastroenterology & Hepatology

ANGPTL2 promotes tumor metastasis in hepatocellular carcinoma

Lin Gao et al.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2015)

Article Biotechnology & Applied Microbiology

Angiopoietin-like protein 2 may mediate the inflammation in murine mastitis through the activation of interleukin-6 and tumour necrosis factor-α

Ji-Ying Wang et al.

WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY (2015)

Article Peripheral Vascular Disease

Angiopoietin-like 7, a novel pro-angiogenetic factor over-expressed in cancer

Matteo Parri et al.

ANGIOGENESIS (2014)

Review Cell Biology

Role of Angptl4 in vascular permeability and inflammation

Liang Guo et al.

INFLAMMATION RESEARCH (2014)

Review Endocrinology & Metabolism

Diverse roles of ANGPTL2 in physiology and pathophysiology

Tsuyoshi Kadomatsu et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2014)

Review Endocrinology & Metabolism

Angiopoietin-like proteins: a comprehensive look

Gaetano Santulli

FRONTIERS IN ENDOCRINOLOGY (2014)

Article Hematology

Overexpression of Angiopoietin-Like Protein 4 Protects Against Atherosclerosis Development

Anastasia Georgiadi et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2013)

Article Biochemistry & Molecular Biology

Angiopoietin-like protein 2, a chronic inflammatory mediator, is a new target induced by TGF-β1 through a Smad3-dependent mechanism

Hee Jae Lee et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)

Review Biochemistry & Molecular Biology

Emerging roles of Lipasin as a critical lipid regulator

Ren Zhang et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)

Article Biochemistry & Molecular Biology

Lipasin, thermoregulated in brown fat, is a novel but atypical member of the angiopoietin-like protein family

Zhiyao Fu et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)

Article Biochemistry & Molecular Biology

Furin Is the Primary in Vivo Convertase of Angiopoietin-like 3 and Endothelial Lipase in Hepatocytes

Rachid Essalmani et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Medicine, Research & Experimental

Angiopoietin-like protein 1 suppresses SLUG to inhibit cancer cell motility

Tsang-Chih Kuo et al.

JOURNAL OF CLINICAL INVESTIGATION (2013)

Article Cardiac & Cardiovascular Systems

Angiopoietin-Like 2 Promotes Atherogenesis in Mice

Nada Farhat et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2013)

Article Biochemistry & Molecular Biology

Lipasin, a novel nutritionally-regulated liver-enriched factor that regulates serum triglyceride levels

Ren Zhang

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)

Review Biochemistry & Molecular Biology

Regulation of triglyceride metabolism by Angiopoietin-like proteins

Frits Mattijssen et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2012)

Review Biochemistry & Molecular Biology

Angiopoietin-like 4: a decade of research

Pengcheng Zhu et al.

BIOSCIENCE REPORTS (2012)

Article Multidisciplinary Sciences

Atypical angiopoietin-like protein that regulates ANGPTL3

Fabiana Quagliarini et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Review Pharmacology & Pharmacy

Integrins as therapeutic targets

Simon L. Goodman et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2012)

Review Biochemistry & Molecular Biology

Mechanisms for the anti-inflammatory effects of statins

De-xiu Bu et al.

CURRENT OPINION IN LIPIDOLOGY (2011)

Article Pharmacology & Pharmacy

Pleiotropic Effects of Nicotinic Acid: Beyond High Density Lipoprotein Cholesterol Elevation

Matilda Florentin et al.

CURRENT VASCULAR PHARMACOLOGY (2011)

Article Endocrinology & Metabolism

Serum levels of angiopoietin-related growth factor are increased in metabolic syndrome

Jun Namkung et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2011)

Article Pathology

Angiopoietin-Like 4 Interacts with Integrins β1 and β5 to Modulate Keratinocyte Migration

Yan Yih Goh et al.

AMERICAN JOURNAL OF PATHOLOGY (2010)

Editorial Material Cell Biology

Fat-Induced Inflammation Unchecked

Olivia Osborn et al.

CELL METABOLISM (2010)

Article Medicine, General & Internal

Exome Sequencing, ANGPTL3 Mutations, and Familial Combined Hypolipidemia

Kiran Musunuru et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Article Gastroenterology & Hepatology

Serum concentrations of human angiopoietin-like protein 3 in patients with nonalcoholic fatty liver disease: association with insulin resistance

Yusuf Yimaz et al.

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY (2009)

Article Biochemical Research Methods

Glycoproteomics Analysis of Human Liver Tissue by Combination of Multiple Enzyme Digestion and Hydrazide Chemistry

Rui Chen et al.

JOURNAL OF PROTEOME RESEARCH (2009)

Review Multidisciplinary Sciences

Origin and physiological roles of inflammation

Ruslan Medzhitov

NATURE (2008)

Review Cardiac & Cardiovascular Systems

The role of angiopoictin-like proteins in angiogenesis and metabolism

Tai Hato et al.

TRENDS IN CARDIOVASCULAR MEDICINE (2008)

Article Multidisciplinary Sciences

Lipid-lowering effects of anti-angiopoietin-like 4 antibody recapitulate the lipid phenotype found in angiopoietin-like 4 knockout mice

Urvi Desai et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Multidisciplinary Sciences

Angiopoietin-like protein 4 converts lipoprotein lipase to inactive monomers and modulates lipase activity in adipose tissue

Valentina Sukonina et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Multidisciplinary Sciences

Cooperative interaction of angiopoietin-like proteins 1 and 2 in zebrafish vascular development

Y Kubota et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Biochemistry & Molecular Biology

Angiopoietin-related growth factor antagonizes obesity and insulin resistance

Y Oike et al.

NATURE MEDICINE (2005)

Article Biochemistry & Molecular Biology

Oligomerization and regulated proteolytic processing of angiopoietin-like protein 4

HF Ge et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

ANGPTL3 decreases very low density lipoprotein triglyceride clearance by inhibition of lipoprotein lipase

T Shimizugawa et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

ANGPTL3 stimulates endothelial cell adhesion and migration via integrin αvβ3 and induces blood vessel formation in vivo

G Camenisch et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

The angiopoietin-like factor cornea-derived transcript 6 is a putative morphogen for human cornea

R Peek et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)