期刊
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
卷 32, 期 15, 页码 1998-2008出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/09205063.2021.1952384
关键词
Methacrylated keratin; hydrogel; photocrosslinking; PEGDMA; biocompatibility
资金
- Jiangsu Higher Education Institutions [19KJA310001]
- Jiangsu Higher Education Institutions [PAPD]
A biocompatible hydrogel was synthesized by blending methacrylated keratin with poly(ethylene glycol dimethacrylate) for tissue engineering and regeneration. The hydrogel exhibited good cytocompatibility, suggesting potential applications in the field.
A biocompatible hydrogel is ideal for tissue engineering and regeneration. In this study, methacrylated keratin (KerMA) was synthesized for the first time and then blended with poly(ethylene glycol dimethacrylate) (PEGDMA) to form hydrogel through photocrosslinking. The chemical structure, gelation time, swelling behavior, hydrophilicity, cytotoxicity, and 3D printability of PEGDMA/KerMA hydrogels were characterized and exploited. The PEGDMA/KerMA hydrogels performed good cytocompatibility, providing potential applications for tissue engineering and regenerative medicine.
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