Euphatexols C - G, five new triterpenoids from the latex of Euphorbia resinifera

Five new triterpenoids named as euphatexols C - G (1-5) were isolated from the latex of Euphorbia resinifera. Their chemical structures were determined by extensive spectroscopic analysis, including IR, HRMS, 1 D and 2 D NMR data. Compounds 1-5 showed moderate anti-inflammatory activity with IC50 values of 22.30, 48.04, 21.89, 38.15 and 41.15 mu M, respectively.

Automated summary

Five new triterpenoids, named as euphatexols C-G (1-5), were isolated from the latex of Euphorbia resinifera. Their chemical structures were determined by extensive spectroscopic analysis. These compounds showed moderate anti-inflammatory activity, with IC50 values ranging from 22.30 to 48.04 µM.