Potential of Olive Oil Mill Wastewater as a Source of Polyphenols for the Treatment of Skin Disorders: A Review

Current trends toward naturally occurring compounds of therapeutic interest have contributed to an increasing number of studies on olive oil phenolics in the treatment of diseases with oxidative and inflammatory origins. Recent focus has been on olive oil wastewater, which is richer in phenolic compounds than olive oil itself. In this review, we present findings demonstrating the potential use of olive mill wastewater in dermatology. Particular attention is given to compounds with proven benefits in topical pharmacology: caffeic and ferulic acids, tyrosol and hydroxytyrosol, verbascoside, and oleuropein. The review is divided into different sections: inflammatory skin diseases, microbial effects, wound healing in addition to the antimelanoma properties of olive mill waste phenolics, and their potential in sun protection agents. There is strong evidence to support further studies into the valorization of this abundant and sustainable source of phenolic compounds for use in dermatology and dermo-cosmetic preparations.

Automated summary

The focus on naturally occurring compounds, particularly olive oil wastewater rich in phenolic compounds, has led to increasing studies on their potential therapeutic benefits in dermatology. Specific attention is given to compounds such as caffeic and ferulic acids, tyrosol and hydroxytyrosol, verbascoside, and oleuropein, which have proven benefits in topical pharmacology. Studies show promising results in the treatment of inflammatory skin diseases, wound healing, antimicrobial effects, and potential as sun protection agents. Further research into the valorization of olive mill waste phenolics for dermatological and dermo-cosmetic applications is strongly supported by existing evidence.