期刊
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
卷 69, 期 30, 页码 8307-8323出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.jafc.1c02653
关键词
food security; CRISPR-Cas system; malnutrition; SDG2; genome editing; new breeding technologies; crop improvement; climate resilient crops
资金
- National Key Science and Technology Program of China [2016YFD0101104]
- Zhejiang Provincial Science and Technology Major Project on Breeding of Agricultural Crops [2016C02050-2]
- China National Key Research and Development program [2020YFE0202300]
- KAUST
Zero hunger is a sustainable development goal set by the United Nations in 2015, and CRISPR-Cas technology has the potential to accelerate the breeding of improved crop varieties to help achieve the goal of zero hunger by 2030.
Zero hunger is one of the sustainable development goals set by the United Nations in 2015 to achieve global food security by 2030. The current harvest of crops is insufficient; feeding the world's population and meeting the goal of zero hunger by 2030 will require larger and more consistent crop production. Clustered regularly interspaced short palindromic repeats-associated protein (CRISPR-Cas) technology is widely used for the plant genome editing. In this review, we consider this technology as a potential tool for achieving zero hunger. We provide a comprehensive overview of CRISPR-Cas technology and its most important applications for food crops' improvement. We also conferred current and potential technological breakthroughs that will help in breeding future crops to end global hunger. The regulatory aspects of deploying this technology in commercial sectors, bioethics, and the production of transgene-free plants are also discussed. We hope that the CRISPR-Cas system will accelerate the breeding of improved crop cultivars compared with conventional breeding and pave the way toward the zero hunger goal.
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