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The impact of COVID-19 on TB: a review of the data

出版社

INT UNION AGAINST TUBERCULOSIS LUNG DISEASE (I U A T L D)
DOI: 10.5588/ijtld.21.0148

关键词

TB; health services; vulnerability; trans-mission; resource

资金

  1. Bill and Melinda Gates Foundation (BMGF), Seattle, WA, USA (TB Modelling and Analysis Consortium) [OPP1135288]
  2. Unitaid Adherence Support Coalition to End TB (ASCENT) project [201933ASCENT]
  3. Wellcome Trust, London, UK [218261/Z/19/Z]
  4. National Institutes of Health, Bethesda, MD, USA [1R01AI14732101]
  5. European & Developing Countries Clinical Trials Partnership, The Hague, The Netherland [RIA208D2505B]
  6. UK Medical Research Council, London, UK (SET Bloomsbury) [CCF17-7779]
  7. Economic and Social Research Council, Swindon, UK [ES/P008011/1]
  8. BMGF [OPP1135288, OPP1084276, INV001754]
  9. WHO, Geneva, Switzerland [2020/9858000]
  10. Wellcome Trust [218261/Z/19/Z] Funding Source: Wellcome Trust

向作者/读者索取更多资源

The COVID-19 pandemic has led to disruptions in TB health services, increased vulnerability to TB, limited evidence on changes in Mycobacterium tuberculosis transmission, and uncertainty about changes in resources needed for the TB response.Improving the available TB data is crucial for advocating for additional funding and efficiently allocating resources for the TB response.
Early in the COVID-19 pandemic, models predicted hundreds of thousands of additional TB deaths as a result of health service disruption. To date, empirical evidence on the effects of COVID-19 on TB outcomes has been limited. Here we summarise the evidence available at a country level, identifying broad mechanisms by which COVID-19 may modify TB burden and mitigation efforts. From the data, it is clear that there have been substantial disruptions to TB health services and an increase in vulnerability to TB. Evidence for changes in Mycobacterium tuberculosis transmission is limited, and it remains unclear how the resources required and available for the TB response have changed. To advocate for additional funding to mitigate the impact of COVID-19 on the global TB burden, and to efficiently allocate resources for the TB response, requires a significant improvement in the TB data available.

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