期刊
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
卷 98, 期 3, 页码 421-427出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/09553002.2021.1980629
关键词
Radiation; biological dosimetry; biomarkers of dose and risk; space flight radiation
资金
- National Institute for Health Research Health Protection Research Unit (NIHR HPRU) in Chemical & Radiation Threats Hazards (NIHR) [NIHR200922]
Ionizing radiation biodosimetry is an exciting field that will benefit from active networking and collaboration with broader fields of radiation research and emergency response. The field will continue to develop to ensure effective, coordinated approaches including emergency dosimetry, radiation epidemiology, personalized medical dosimetry, and space travel.
Purpose: The aim of this brief personal, high level review is to consider the state of the art for biological dosimetry for radiation routine and emergency response, and the potential future progress in this fascinating and active field. Four areas in which biomarkers may contribute to scientific advancement through improved dose and exposure characterization, as well as potential contributions to personalized risk estimation, are considered: emergency dosimetry, molecular epidemiology, personalized medical dosimetry, and space travel. Conclusion: Ionizing radiation biodosimetry is an exciting field which will continue to benefit from active networking and collaboration with the wider fields of radiation research and radiation emergency response to ensure effective, joined up approaches to triage; radiation epidemiology to assess long term, low dose, radiation risk; radiation protection of workers, optimization and justification of radiation for diagnosis or treatment of patients in clinical uses, and protection of individuals traveling to space.
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