4.2 Article

Saliva cortisol levels and physiological parameter fluctuations in mild traumatic brain injury patients compared to controls

期刊

INTERNATIONAL JOURNAL OF NEUROSCIENCE
卷 133, 期 6, 页码 612-620

出版社

TAYLOR & FRANCIS LTD
DOI: 10.1080/00207454.2021.1951264

关键词

Body temperature; blood pressure; fluctuations; heart rate; saliva cortisol levels; traumatic brain injury

向作者/读者索取更多资源

Fluctuations of cortisol and physiological parameters increase during the acute phase of mTBI, which may affect sleep quality.
Background: Evidence suggests that fluctuations of cortisol and physiological parameters can emerge during the course of mild Traumatic Brain Injury (mTBI). Objective: To investigate fluctuations of cortisol and physiological parametersduring the acute phase of mTBI in hospitalized patients. Methods: 30 participants (19 patients with mTBI and 11 controls) were examined for saliva cortisol dynamics, heart rate (HR), systolic arterial pressure (SAP), diastolic arterial pressure (DAP), mean arterial pressure (MAP) and body temperature (BT) fluctuations for four consecutive days. Also, the participants completed the Athens Insomnia Scale and Epworth Sleepiness Scales, in order to check for sleep problems. Results: Patients showed elevated levels of cortisol relative to controls (peak at 8 am and lowest levels at 12 am), as well as for most physiological parameters. MAP was significantly higher for patients throughout the measurement period, and BT was elevated for patients relative to controls at almost all measurements of the first and second day. Mean HR tended to track at non-significantly higher levels for the mTBI group. Patients' sleepiness and insomnia values (ESS and AIS) were initially significantly higher relative to controls but the difference dissipated by day 4. Conclusion: The increase in absolute values of cortisol and physiological parameters measurements, indicates that in the acute phase of mTBI, a stressful process is activated which may affect sleep quality as well. Supplemental data for this article is available online at at doi: 10.1080/00207454.2021.1951264.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.2
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据