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LANCET NEUROLOGY (2009)
I-123-Metaiodobenzylguanidine Scintigraphy in Parkinson's Disease and Related Disorders
Olivier Rascol et al.
MOVEMENT DISORDERS (2009)
Substantia Nigra Echogenicity: A Structural Correlate of Functional Impairment of the Dopaminergic Striatal Projection in Parkinson's Disease
David Weise et al.
MOVEMENT DISORDERS (2009)
Transmission and spreading of tauopathy in transgenic mouse brain
Florence Clavaguera et al.
NATURE CELL BIOLOGY (2009)
Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates
Pei-Hsien Ren et al.
NATURE CELL BIOLOGY (2009)
Course in Parkinson disease subtypes A 39-year clinicopathologic study
A. H. Rajput et al.
NEUROLOGY (2009)
Neuropathology of non-motor features of Parkinson disease
Dennis W. Dickson et al.
PARKINSONISM & RELATED DISORDERS (2009)
Exogenous α-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells
Kelvin C. Luk et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
A Critical Evaluation of the Braak Staging Scheme for Parkinson's Disease
Robert E. Burke et al.
ANNALS OF NEUROLOGY (2008)
Diffusion-weighted brain imaging study of patients with clinical diagnosis of corticobasal degeneration, progressive supranuclear palsy and Parkinson's disease
Giovanni Rizzo et al.
BRAIN (2008)
Relationship of phosphorylated α-synuclein and tau accumulation to Aβ deposition in the cerebral cortex of dementia with Lewy bodies
Kimiko Obi et al.
EXPERIMENTAL NEUROLOGY (2008)
Mitochondria in the aetiology and pathogenesis of Parkinson's disease
Anthony H. V. Schapira
LANCET NEUROLOGY (2008)
Nigral burden of α-synuclein correlates with striatal dopamine deficit
Gabor G. Kovacs et al.
MOVEMENT DISORDERS (2008)
Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
Jia-Yi Li et al.
NATURE MEDICINE (2008)
Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease
Jeffrey H. Kordower et al.
NATURE MEDICINE (2008)
The dorsal motor nucleus of the vagus is not an obligatory trigger site of Parkinson's disease:: a critical analysis of α-synuclein staging
M. E. Kalaitzakis et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2008)
Phosphorylation of tau and α-synuclein in synaptic-enriched fractions of the frontal cortex in Alzheimer's disease, and in Parkinson's disease and related α-synucleinopathies
G. Muntane et al.
NEUROSCIENCE (2008)
Clinical aspects of bowel symptoms in Parkinson's disease
K. Krogh et al.
ACTA NEUROLOGICA SCANDINAVICA (2008)
Parkinson's disease: a dual-hit hypothesis
C. H. Hawkes et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2007)
Marked microglial reaction in normal aging human substantia nigra: correlation with extraneuronal neuromelanin pigment deposits
Thomas G. Beach et al.
ACTA NEUROPATHOLOGICA (2007)
'Rejuvenation' protects neurons in mouse models of Parkinson's disease
C. Savio Chan et al.
NATURE (2007)
Roles of subthreshold calcium current and sodium current in spontaneous firing of mouse midbrain dopamine neurons
Michelino Puopolo et al.
JOURNAL OF NEUROSCIENCE (2007)
Expression of Nrf2 in neurodegenerative diseases
Chenere P. Ramsey et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2007)
Relating mode of action to clinical practice: Dopaminergic agents in Parkinson's disease
Peter Riederer et al.
PARKINSONISM & RELATED DISORDERS (2007)
Striatal dopaminergic neurons are lost with Parkinson's disease progression
Michelle J. Porritt et al.
MOVEMENT DISORDERS (2006)
Exogenous induction of cerebral β-amyloidogenesis is governed by agent and host
Melanie Meyer-Luehmann et al.
SCIENCE (2006)
Helicobacter pylori eradication and L-dopa absorption in patients with PD and motor fluctuations
M. Pierantozzi et al.
NEUROLOGY (2006)
Is neuromelanin changed in Parkinson's disease? Investigations by magnetic spectroscopies
M Fasano et al.
JOURNAL OF NEURAL TRANSMISSION (2006)
Gastric α-synuclein immunoreactive inclusions in Meissner's and Auerbach's plexuses in cases staged for Parkinson's disease-related brain pathology
H Braak et al.
NEUROSCIENCE LETTERS (2006)
P25α stimulates a-synuclein aggregation and is co-localized with aggregated α-synuclein in α-synucleinopathies
E Lindersson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Release of long-range tertiary interactions potentiates aggregation of natively unstructured α-synuclein
CW Bertoncini et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Alpha-synuclein lesions in normal aging, Parkinson disease, and Alzheimer disease: Evidence from the Baltimore Longitudinal Study of Aging (BLSA)
I Mikolaenko et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2005)
Mapping long-range interactions in α-synuclein using spin-label NMR and ensemble molecular dynamics simulations
MM Dedmon et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
The new mutation, E46K, of α-synuclein causes Parkinson and Lewy body dementia
JJ Zarranz et al.
ANNALS OF NEUROLOGY (2004)
Ubiquitination of α-synuclein in Lewy bodies is a pathological event not associated with impairment of proteasome function
GK Tofaris et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
α-synuclein locus triplication causes Parkinson's disease
AB Singleton et al.
SCIENCE (2003)
Polycation-induced oligomerization and accelerated fibrillation of human α-synuclein in vitro
J Goers et al.
PROTEIN SCIENCE (2003)
Conformational behavior and aggregation of α-synuclein in organic solvents:: Modeling the effects of membranes
LA Munishkina et al.
BIOCHEMISTRY (2003)
Staging of brain pathology related to sporadic Parkinson's disease
H Braak et al.
NEUROBIOLOGY OF AGING (2003)
The formation of highly soluble oligomers of α-synuclein is regulated by fatty acids and enhanced in Parkinson's disease
R Sharon et al.
NEURON (2003)
Phosphorylated α-synuclein is ubiquitinated in α-synucleinopathy lesions
M Hasegawa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Ageing of substantia nigra in humans: cell loss may be compensated by hypertrophy
CR Cabello et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2002)
Differential neuropathological alterations in transgenic mice expressing α-synuclein from the platelet-derived growth factor and Thy-1 promoters
E Rockenstein et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2002)
Elevated glial brain-derived neurotrophic factor in Parkinson's diseased nigra
C Knott et al.
PARKINSONISM & RELATED DISORDERS (2002)
Neuronal α-synucleinopathy with severe movement disorder in mice expressing A53T human α-synuclein
BI Giasson et al.
NEURON (2002)
Molecular crowding accelerates fibrillization of α-synuclein:: Could an increase in the cytoplasmic protein concentration induce Parkinson's disease?
MD Shtilerman et al.
BIOCHEMISTRY (2002)
Heparin and other glycosaminoglycans stimulate the formation of amyloid fibrils from α-synuclein in vitro
JA Cohlberg et al.
BIOCHEMISTRY (2002)
α-Synuclein is phosphorylated in synucleinopathy lesions
H Fujiwara et al.
NATURE CELL BIOLOGY (2002)
Metal-triggered structural transformations, aggregation, and fibrillation of human α-synuclein -: A possible molecular link between Parkinson's disease and heavy metal exposure
VN Uversky et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Pesticides directly accelerate the rate of α-synuclein fibril formation:: a possible factor in Parkinson's disease
VN Uversky et al.
FEBS LETTERS (2001)
Evidence for a partially folded intermediate in α-synuclein fibril formation
VN Uversky et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Activated Fyn phosphorylates α-synuclein at tyrosine residue 125
T Nakamura et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2001)
A hydrophobic stretch of 12 amino acid residues in the middle of α-synuclein is essential for filament assembly
BI Giasson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Oxidative damage linked to neurodegeneration by selective α-synuclein nitration in synucleinopathy lesions
BI Giasson et al.
SCIENCE (2000)
Chaperone-like activity of synucleins
JM Souza et al.
FEBS LETTERS (2000)
Parkinson's disease:: affection of brain stem nuclei controlling premotor and motor neurons of the somatomotor system
H Braak et al.
ACTA NEUROPATHOLOGICA (2000)
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