☆ 4.7 Review

The Emerging Role of Neutrophils in the Pathogenesis of Thrombosis in COVID-19

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

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Summary: Kawasaki disease (KD) is a systemic vasculitis that predominantly affects medium- and small-sized muscular arteries. The histopathologic study revealed infiltration of cytotoxic protein-positive cells, including CD8(+) T cells, which may play a role in the development of vasculitis lesions in KD patients.

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TLR4 regulates ROS and autophagy to control neutrophil extracellular traps formation againstStreptococcus pneumoniaein acute otitis media

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Summary: This study found that autophagy and ROS are required for S.pn-induced NETs formation in the model of acute otitis media (AOM). TLR4 partially mediated NETs formation during AOM. The research may provide a potential strategy for the treatment of otitis media.

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High D dimers and low global fibrinolysis coexist in COVID19 patients: what is going on in there?

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Impact of convalescent and nonimmune plasma on mortality of patients with COVID-19: a potential role for antithrombin

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Immunothrombosis and thromboinflammation in host defense and disease

Kimberly Martinod et al.

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Katja Evert et al.

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Atieh Darbandi et al.

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INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2021)

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FRONTIERS IN CARDIOVASCULAR MEDICINE (2019)

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Corticosteroid Therapy for Critically Ill Patients with Middle East Respiratory Syndrome

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AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2018)

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Review Hematology

The Pathophysiological Role of Neutrophil Extracellular Traps in Inflammatory Diseases

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THROMBOSIS AND HAEMOSTASIS (2018)

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Maladaptive role of neutrophil extracellular traps in pathogen-induced lung injury

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JCI INSIGHT (2018)

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DNA-fragmentation is a source of bactericidal activity against Pseudomonas aeruginosa

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Update on colchicine, 2017

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Neutrophil extracellular trap formation upon exposure of hydrophobic materials to human whole blood causes thrombogenic reactions

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BIOMATERIALS SCIENCE (2017)

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Article Microbiology

Immunomodulatory Role of Clarithromycin in Acinetobacter baumannii Infection via Formation of Neutrophil Extracellular Traps

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ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2016)

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Review Critical Care Medicine

Prolonged glucocorticoid treatment is associated with improved ARDS outcomes: analysis of individual patients' data from four randomized trials and trial-level meta-analysis of the updated literature

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Article Critical Care Medicine

Distinct Molecular Phenotypes of Direct vs Indirect ARDS in Single-Center and Multicenter Studies

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CHEST (2015)

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Article Immunology

Neutrophil extracellular trap formation is associated with autophagy-related signalling in ANCA-associated vasculitis

S. Tang et al.

CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2015)

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Article Cardiac & Cardiovascular Systems

Expression of functional tissue factor by neutrophil extracellular traps in culprit artery of acute myocardial infarction

Dimitrios A. Stakos et al.

EUROPEAN HEART JOURNAL (2015)

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Article Multidisciplinary Sciences

Neutrophil Responses to Sterile Implant Materials

Siddharth Jhunjhunwala et al.

PLOS ONE (2015)

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Article Microbiology

DNA Is an Antimicrobial Component of Neutrophil Extracellular Traps

Tyler W. R. Halverson et al.

PLOS PATHOGENS (2015)

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Article Immunology

NET formation induced by Pseudomonas aeruginosa cystic fibrosis isolates measured as release of myeloperoxidase-DNA and neutrophil elastase-DNA complexes

Dae-Goon Yoo et al.

IMMUNOLOGY LETTERS (2014)

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Article Immunology

Probiotic Lactobacillus rhamnosus Inhibits the Formation of Neutrophil Extracellular Traps

Linda Vong et al.

JOURNAL OF IMMUNOLOGY (2014)

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Article Virology

Possible Involvement of Infection With Human Coronavirus 229E, but not NL63, in Kawasaki Disease

Kazuya Shirato et al.

JOURNAL OF MEDICAL VIROLOGY (2014)

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Article Hematology

Neutrophil extracellular traps promote deep vein thrombosis in mice

A. Brill et al.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2012)

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Article Multidisciplinary Sciences

Autophagy Mediates the Delivery of Thrombogenic Tissue Factor to Neutrophil Extracellular Traps in Human Sepsis

Konstantinos Kambas et al.

PLOS ONE (2012)

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Review Physiology

The Link Between Vascular Features and Thrombosis

Charles T. Esmon et al.

ANNUAL REVIEW OF PHYSIOLOGY, VOL 73 (2011)

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Polyphosphate is a cofactor for the activation of factor XI by thrombin

Sharon H. Choi et al.

BLOOD (2011)

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Article Multidisciplinary Sciences

Neutrophil Extracellular Trap Formation Is Associated with IL-1β and Autophagy-Related Signaling in Gout

Ioannis Mitroulis et al.

PLOS ONE (2011)

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Article Cell Biology

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

Venizelos Papayannopoulos et al.

JOURNAL OF CELL BIOLOGY (2010)

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Article Immunology

PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps

Pingxin Li et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2010)

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Article Immunology

A Novel Mechanism of Rapid Nuclear Neutrophil Extracellular Trap Formation in Response to Staphylococcus aureus

Florian H. Pilsczek et al.

JOURNAL OF IMMUNOLOGY (2010)

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Article Hematology

Restoration of NET formation by gene therapy in CGD controls aspergillosis

Matteo Bianchi et al.

BLOOD (2009)

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Article Immunology

C5a and TNF-α up-regulate the expression of tissue factor in intra-alveolar neutrophils of patients with the acute respiratory distress syndrome

Konstantinos Kambas et al.

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Article Hematology

Granulocytes do not express but acquire monocyte-derived tissue factor in whole blood: evidence for a direct transfer

Elena M. Egorina et al.

BLOOD (2008)

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Review Microbiology

Beneficial suicide: why neutrophils die to make NETs

Volker Brinkmann et al.

NATURE REVIEWS MICROBIOLOGY (2007)

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Review Hematology

Neutrophil activation via β2 integrins (CD11/CD18):: Molecular mechanisms and clinical implications

Jorgen Schymeinsky et al.

THROMBOSIS AND HAEMOSTASIS (2007)

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Novel cell death program leads to neutrophil extracellular traps

Tobias A. Fuchs et al.

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Neutrophil extracellular traps capture and kill Candida albicans yeast and hyphal forms

CF Urban et al.

CELLULAR MICROBIOLOGY (2006)

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Neutrophil extracellular traps kill bacteria

V Brinkmann et al.

SCIENCE (2004)

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Nuclear localization of peptidylarginine deiminase V and histone deimination in granulocytes

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Review Pharmacology & Pharmacy

The role of neutrophil elastase in acute lung injury

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