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Fatty Acid Synthesis in Glial Cells of the CNS

期刊

出版社

MDPI
DOI: 10.3390/ijms22158159

关键词

fatty acids; glia; central nervous system; neurological disease; CNS repair

资金

  1. Charcot Research Foundation [R-8676, R-6832, FCS-2016-EG7]
  2. Research Foundation Flanders (FWO) [12J9116N, 12JG119N, G099618N]
  3. Interreg V-A EMR program (EURLIPIDS) [EMR23]

向作者/读者索取更多资源

Fatty acids play a crucial role in brain homeostasis and neural function, with glia cells supporting the high demand of FAs in the CNS. Modulating FA synthesis in glia presents a potential therapeutic opportunity for various CNS diseases, including Alzheimer's and multiple sclerosis.
Fatty acids (FAs) are of crucial importance for brain homeostasis and neural function. Glia cells support the high demand of FAs that the central nervous system (CNS) needs for its proper functioning. Additionally, FAs can modulate inflammation and direct CNS repair, thereby contributing to brain pathologies such Alzheimer's disease or multiple sclerosis. Intervention strategies targeting FA synthesis in glia represents a potential therapeutic opportunity for several CNS diseases.

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