4.7 Article

Chlorogenic Acid Enhances Doxorubicin-Mediated Cytotoxic Effect in Osteosarcoma Cells

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Chlorogenic acid induces 4T1 breast cancer tumor's apoptosis via p53, Bax, Bcl-2, and caspase-3 signaling pathways in BALB/c mice

Zahra Changizi et al.

Summary: Chlorogenic acid (CGA) shows significant effects in inducing apoptosis and treating 4T1 breast cancer tumors in BALB/c mice, reducing tumor weight and volume, decreasing metastatic nodules, promoting apoptosis, and increasing the expression levels of specific genes.

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY (2021)

Article Oncology

Chlorogenic acid induces apoptosis, inhibits metastasis and improves antitumor immunity in breast cancer via the NF-kappa B signaling pathway

Anqi Zeng et al.

Summary: The study demonstrated that chlorogenic acid (CGA), a potent NF-kappa B inhibitor derived from coffee, exerted anti-tumor and anti-metastatic effects in breast cancer treatment by significantly inhibiting the viability and proliferation of breast cancer cells and improving anti-tumor immunity by impairing the NF-kappa B/EMT signaling pathway.

ONCOLOGY REPORTS (2021)

Review Oncology

Recent Insights into Therapy Resistance in Osteosarcoma

Zachary D. Prudowsky et al.

Summary: Osteosarcoma is the most common bone malignancy of childhood. Standard chemotherapy regimens work well for many patients, but there are minimal options for patients with progressive or resistant disease. A better understanding of therapy resistance is necessary to improve current treatments and design new strategies for future treatment options.

CANCERS (2021)

Article Biochemistry & Molecular Biology

Chlorogenic acid inhibits proliferation in human hepatoma cells by suppressing noncanonical NF-κB signaling pathway and triggering mitochondrial apoptosis

Yanfei Jiang et al.

Summary: Chlorogenic acid (CGA), a compound derived from Eucommia ulmoides, has exhibited potent cytotoxic and anti-proliferative activities against various human cancers, particularly hepatocellular carcinoma (HCC). Through modulation of multiple pharmacological signaling pathways, CGA effectively inhibits hepatoma cell activity and promotes mitochondrial apoptosis in HCC.

MOLECULAR BIOLOGY REPORTS (2021)

Review Medicine, Research & Experimental

A comprehensive review on time-tested anticancer drug doxorubicin

Sruthi Sritharan et al.

Summary: Doxorubicin is a widely used chemotherapeutic drug for cancer treatment, inducing cell death through various mechanisms and aiding in immune clearance of tumor cells, but its applicability is limited by the development of chemoresistance and cardiotoxicity. Various formulations and co-treatments are essential in reducing toxicity and combating resistance. Further research into the molecular mechanisms of chemoresistance development is crucial for improving patient survivability and preventing cancer relapse.

LIFE SCIENCES (2021)

Review Biochemistry & Molecular Biology

Therapeutic Promises of chlorogenic Acid Emphasis on its Anti-Obesity Property

Rajnish Kumar et al.

CURRENT MOLECULAR PHARMACOLOGY (2020)

Review Pharmacology & Pharmacy

Natural compounds as potential adjuvants to cancer therapy: Preclinical evidence

Shian-Ren Lin et al.

BRITISH JOURNAL OF PHARMACOLOGY (2020)

Article Cell Biology

Chlorogenic acid activates ERK1/2 and inhibits proliferation of osteosarcoma cells

Luigi Sapio et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2020)

Review Biochemistry & Molecular Biology

Targeting MAPK Signaling in Cancer: Mechanisms of Drug Resistance and Sensitivity

Shannon Lee et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Chemistry, Multidisciplinary

sFRP1 protects H9c2 cardiac myoblasts from doxorubicin-induced apoptosis by inhibiting the Wnt/PCP-JNK pathway

Yue-huai Hu et al.

ACTA PHARMACOLOGICA SINICA (2020)

Review Chemistry, Medicinal

Antitumour Anthracyclines: Progress and Perspectives

Maristela B. Martins-Teixeira et al.

CHEMMEDCHEM (2020)

Article Biochemistry & Molecular Biology

Targeted MEK inhibition by cobimetinib enhances doxorubicin's efficacy in osteosarcoma models

Liang Ma et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2020)

Article Pharmacology & Pharmacy

The Prophylactic Effect of Pinocembrin Against Doxorubicin-Induced Cardiotoxicity in anIn VitroH9c2 Cell Model

Nonhlakanipho F. Sangweni et al.

FRONTIERS IN PHARMACOLOGY (2020)

Review Biochemistry & Molecular Biology

Anti-Cancer Effects of Green Tea Epigallocatchin-3-Gallate and Coffee Chlorogenic Acid

Sumio Hayakawa et al.

MOLECULES (2020)

Article Biochemical Research Methods

Multiobjective optimization identifies cancer-selective combination therapies

Otto I. Pulkkinen et al.

PLOS COMPUTATIONAL BIOLOGY (2020)

Review Biochemistry & Molecular Biology

Targeting cancer stem cell pathways for cancer therapy

Liqun Yang et al.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2020)

Article Biotechnology & Applied Microbiology

Chlorogenic Acid Attenuates Dextran Sodium Sulfate-Induced Ulcerative Colitis in Mice through MAPK/ERK/JNK Pathway

Wenyan Gao et al.

BIOMED RESEARCH INTERNATIONAL (2019)

Review Multidisciplinary Sciences

A view on drug resistance in cancer

Neil Vasan et al.

NATURE (2019)

Article Biochemistry & Molecular Biology

Chlorogenic acid inhibits osteosarcoma carcinogenesis via suppressing the STAT3/Snail pathway

Fang Zhang et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2019)

Review Oncology

Current and future therapeutic approaches for osteosarcoma

Douglas J. Harrison et al.

EXPERT REVIEW OF ANTICANCER THERAPY (2018)

Review Pharmacology & Pharmacy

Advances in nano-delivery systems for doxorubicin: an updated insight

Ummarah Kanwal et al.

JOURNAL OF DRUG TARGETING (2018)

Review Medicine, Research & Experimental

Chlorogenic acid (CGA): A pharmacological review and call for further research

Muhammad Naveed et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

Article Biochemistry & Molecular Biology

Chlorogenic Acid and Its Microbial Metabolites Exert Anti -Proliferative Effects, S-Phase Cell-Cycle Arrest and Apoptosis in Human Colon Cancer Caco-2 Cells

Shima Sadeghi Ekbatan et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Review Biochemistry & Molecular Biology

Anthracyclines as Topoisomerase II Poisons: From Early Studies to New Perspectives

Jessica Marinello et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Review Pharmacology & Pharmacy

Evolution of Cancer Pharmacological Treatments at the Turn of the Third Millennium

Luca Falzone et al.

FRONTIERS IN PHARMACOLOGY (2018)

Review Biochemistry & Molecular Biology

Natural Compounds from Herbs that can Potentially Execute as Autophagy Inducers for Cancer Therapy

Shian-Ren Lin et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Article Medicine, General & Internal

Long-Term and Latent Side Effects of Specific Cancer Types

Nana Gegechkori et al.

MEDICAL CLINICS OF NORTH AMERICA (2017)

Review Cell Biology

ROS and ROS-Mediated Cellular Signaling

Jixiang Zhang et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)

Review Cell Biology

ERK1 and ERK2 Map Kinases: Specific Roles or Functional Redundancy?

Roser Busca et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2016)

Article Chemistry, Multidisciplinary

Protective effect of Mutellina purpurea polyphenolic compounds in doxorubicin-induced toxicity in H9c2 cardiomyocytes

Slawomir Mandziuk et al.

DRUG AND CHEMICAL TOXICOLOGY (2015)

Review Chemistry, Multidisciplinary

Doxil® - The first FDA-approved nano-drug: Lessons learned

Yechezkel (Chezy) Barenholz

JOURNAL OF CONTROLLED RELEASE (2012)

Article Pathology

Mitogen-activated protein kinase pathway in osteosarcoma

Ki Yong Na et al.

PATHOLOGY (2012)

Article Orthopedics

Targeting Inflammatory Kinase as an Adjuvant Treatment for Osteosarcomas

Kyucheol Noh et al.

JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME (2011)

Article Medicine, Research & Experimental

Functional characterization of osteosarcoma cell lines provides representative models to study the human disease

Alexander B. Mohseny et al.

LABORATORY INVESTIGATION (2011)