相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Locking up the AS1411 Aptamer with a Flanking Duplex: Towards an Improved Nucleolin-Targeting
Andre Miranda et al.
PHARMACEUTICALS (2021)
Overview of the Therapeutic Potential of Aptamers Targeting Coagulation Factors
Max Liu et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Bimodular thrombin aptamers with two types of non-covalent locks
Rugiya Alieva et al.
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS (2021)
Thrombin-Binding Aptamer with Inversion of Polarity Sites (IPS): Effect on DNAzyme Activity and Anticoagulant Properties
Joanna Kosman et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
DNA G-quadruplex structures: more than simple roadblocks to transcription?
Jenna Robinson et al.
NUCLEIC ACIDS RESEARCH (2021)
Fine-tuning the properties of the thrombin binding aptamer through cyclization: Effect of the 5 '-3 ' connecting linker on the aptamer stability and anticoagulant activity
Claudia Riccardi et al.
BIOORGANIC CHEMISTRY (2020)
Specific Binding of a d-RNA G-Quadruplex Structure with an l-RNA Aptamer
Chun-Yin Chan et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)
Thrombin binding aptamer G-quadruplex stabilized by pyrene-modified nucleotides
Matic Kovacic et al.
NUCLEIC ACIDS RESEARCH (2020)
Short Duplex Module Coupled to G-Quadruplexes Increases Fluorescence of Synthetic GFP Chromophore Analogues
Snizhana O. Zaitseva et al.
SENSORS (2020)
Methoxymethyl Threofuranosyl Thymidine (4′-MOM-TNA-T) at the T7 Position of the Thrombin-Binding Aptamer Boosts Anticoagulation Activity, Thermal Stability, and Nuclease Resistance
Manojkumar Varada et al.
ACS OMEGA (2020)
Development and structural determination of an anti-PrPC aptamer that blocks pathological conformational conversion of prion protein
Tsukasa Mashima et al.
SCIENTIFIC REPORTS (2020)
Design, Synthesis and Characterization of Cyclic NU172 Analogues: A Biophysical and Biological Insight
Claudia Riccardi et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Quadruplex-Duplex Junction: A High-Affinity Binding Site for Indoloquinoline Ligands
Yoanes Maria Vianney et al.
CHEMISTRY-A EUROPEAN JOURNAL (2020)
Improved Anti-Prion Nucleic Acid Aptamers by Incorporation of Chemical Modifications
Jussara Amato et al.
NUCLEIC ACID THERAPEUTICS (2020)
Improved RE31 Analogues Containing Modified Nucleic Acid Monomers: Thermodynamic, Structural, and Biological Effects
Weronika Kotkowiak et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
Rapidly Neutralizable and Highly Anticoagulant Thrombin-Binding DNA Aptamer Discovered by MACE SELEX
Koji Wakui et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2019)
A structure-activity relationship of a thrombin-binding aptamer containing LNA in novel sites
GuoQing Ying et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2019)
Investigating the properties of TBA variants with twin thrombin binding domains
Teresa Amato et al.
SCIENTIFIC REPORTS (2019)
Bimodular Antiparallel G-Quadruplex Nanoconstruct with Antiproliferative Activity
Olga Antipova et al.
MOLECULES (2019)
Aptamer-guided acridine derivatives for cervical cancer
Josue Carvalho et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2019)
Duplex/quadruplex oligonucleotides: Role of the duplex domain in the stabilization of a new generation of highly effective anti-thrombin aptamers
Irene Russo Krauss et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)
Novel isoguanine derivative of unlocked nucleic acid-Investigations of thermodynamics and biological potential of modified thrombin binding aptamer
Weronika Kotkowiak et al.
PLOS ONE (2018)
Improvement of the activity of the anti-HIV-1 integrase aptamer T30175 by introducing a modified thymidine into the loops
Antonella Virgilio et al.
SCIENTIFIC REPORTS (2018)
Thermodynamic, Anticoagulant, and Antiproliferative Properties of Thrombin Binding Aptamer Containing Novel UNA Derivative
Weronika Kotkowiak et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2018)
Several structural motifs cooperate in determining the highly effective anti-thrombin activity of NU172 aptamer
Romualdo Troisi et al.
NUCLEIC ACIDS RESEARCH (2018)
Construction of a Bivalent Thrombin Binding Aptamer and Its Antidote with Improved Properties
Quintin W. Hughes et al.
MOLECULES (2017)
Triplex-quadruplex structural scaffold: a new binding structure of aptamer
Tao Bing et al.
SCIENTIFIC REPORTS (2017)
The Bioactivity of D-/L-Isonucleoside- and 2′-Deoxyinosine-Incorporated Aptamer AS1411s Including DNA Replication/MicroRNA Expression
Xinmeng Fan et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2017)
G-quadruplex oligonucleotide AS1411 as a cancer-targeting agent: Uses and mechanisms
Paula J. Bates et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2017)
Different duplex/quadruplex junctions determine the properties of anti-thrombin aptamers with mixed folding
Irene Russo Krauss et al.
NUCLEIC ACIDS RESEARCH (2016)
Metal Cations in G-Quadruplex Folding and Stability
Debmalya Bhattacharyya et al.
FRONTIERS IN CHEMISTRY (2016)
Modified AS1411 Aptamer Suppresses Hepatocellular Carcinoma by Up-Regulating Galectin-14
Yuri Cho et al.
PLOS ONE (2016)
Bioactivity of 2′-deoxyinosine-incorporated aptamer AS1411
Xinmeng Fan et al.
SCIENTIFIC REPORTS (2016)
Parallel G-quadruplexes formed by guanine-rich microsatellite repeats inhibit human topoisomerase I
A. M. Ogloblina et al.
BIOCHEMISTRY-MOSCOW (2015)
Current approaches in SELEX: An update to aptamer selection technology
Mariia Darmostuk et al.
BIOTECHNOLOGY ADVANCES (2015)
A target-induced three-way G-quadruplex junction for 17β-estradiol monitoring with a naked-eye readout
Junhua Chen et al.
CHEMICAL COMMUNICATIONS (2015)
A family of DNA aptamers with varied duplex region length that forms complexes with thrombin and prothrombin
V. A. Spiridonova et al.
FEBS LETTERS (2015)
Structure variations of TBA G-quadruplex induced by 2'-O-methyl nucleotide in K+ and Ca2+ environments
Xiaoyang Zhao et al.
ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2014)
Unlocked nucleic acids: implications of increased conformational flexibility for RNA/DNA triplex formation
Weronika Kotkowiak et al.
BIOCHEMICAL JOURNAL (2014)
Functional isoDNA aptamers: modified thrombin binding aptamers with a 2'-5'-linked sugarphosphate backbone (isoTBA)
Anita D. Gunjal et al.
CHEMICAL COMMUNICATIONS (2014)
A straightforward modification in the thrombin binding aptamer improving the stability, affinity to thrombin and nuclease resistance
Veronica Esposito et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2014)
Nucleic Acid Aptamers: Research Tools in Disease Diagnostics and Therapeutics
Baby Santosh et al.
BIOMED RESEARCH INTERNATIONAL (2014)
Duplex-quadruplex motifs in a peculiar structural organization cooperatively contribute to thrombin binding of a DNA aptamer
Irene Russo Krauss et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2013)
Structural Basis of DNA Quadruplex-Duplex Junction Formation
Kah Wai Lim et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)
Aptamer RA36 Inhibits of Human, Rabbit, and Rat Plasma Coagulation Activated with Thrombin or Snake Venom Coagulases
E. Yu. Savchik et al.
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE (2013)
Dissecting the contribution of thrombin exosite I in the recognition of thrombin binding aptamer
Andrea Pica et al.
FEBS JOURNAL (2013)
Aptamers: multifunctional molecules for biomedical research
Jayeeta Banerjee et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2013)
G-quadruplex DNA Aptamers and their Ligands: Structure, Function and Application
W. O. Tucker et al.
CURRENT PHARMACEUTICAL DESIGN (2012)
Coexistence of G-quadruplex and duplex domains within the secondary structure of 31-mer DNA thrombin-binding aptamer
N. G. Dolinnaya et al.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2012)
DNA secondary structures: stability and function of G-quadruplex structures
Matthew L. Bochman et al.
NATURE REVIEWS GENETICS (2012)
High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity
Irene Russo Krauss et al.
NUCLEIC ACIDS RESEARCH (2012)
Thermodynamic and biological evaluation of a thrombin binding aptamer modified with several unlocked nucleic acid (UNA) monomers and a 2′-C-piperazino-UNA monomer
Troels B. Jensen et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2011)
The circular dichroism and differential scanning calorimetry study of the properties of DNA aptamer dimers
Slavomira Ponikova et al.
BIOPHYSICAL CHEMISTRY (2011)
Characteristics of a New DNA Aptamer, Direct Inhibitor of Thrombin
A. V. Mazurov et al.
BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE (2011)
Novel Modular DNA Aptamer for Human Thrombin with High Anticoagulant Activity
E. Zavyalova et al.
CURRENT MEDICINAL CHEMISTRY (2011)
Nucleic Acid Aptamers: Clinical Applications and Promising New Horizons
X. Ni et al.
CURRENT MEDICINAL CHEMISTRY (2011)
Improved thrombin binding aptamer by incorporation of a single unlocked nucleic acid monomer
Anna Pasternak et al.
NUCLEIC ACIDS RESEARCH (2011)
HIV-1 integrase inhibitor T30177 forms a stacked dimeric G-quadruplex structure containing bulges
Vineeth Thachappilly Mukundan et al.
NUCLEIC ACIDS RESEARCH (2011)
Direct Detection of Thrombin Binding to 8-Bromodeoxyguanosine-Modified Aptamer: Effects of Modification on Affinity and Kinetics
Shou Goji et al.
JOURNAL OF NUCLEIC ACIDS (2011)
Conformation and thermostability of oligonucleotide d(GGTTGGTGTGGTTGG) containing thiophosphoryl internucleotide bonds at different positions
Marina Zaitseva et al.
BIOPHYSICAL CHEMISTRY (2010)
Resolution and characterization of the structural polymorphism of a single quadruplex-forming sequence
Magdalena M. Dailey et al.
NUCLEIC ACIDS RESEARCH (2010)
The effect of DNA aptamer configuration on the sensitivity of detection thrombin at surface by acoustic method
Tibor Hianik et al.
CHEMICAL COMMUNICATIONS (2009)
A Grafting Strategy for the Design of Improved G-Quadruplex Aptamers and High-Activity DNAzymes
Tao Li et al.
PLOS ONE (2009)
Anticoagulant characteristics of HD1-22, a bivalent aptamer that specifically inhibits thrombin and prothrombinase
J. Mueller et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2008)
Novel bimodular DNA aptamers with guanosine quadruplexes inhibit phylogenetically diverse HIV-1 reverse transcriptases
Daniel Michalowski et al.
NUCLEIC ACIDS RESEARCH (2008)
Molecular assembly for high-performance bivalent nucleic acid inhibitor
Youngmi Kim et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Improvement of aptamer affinity by dimerization
Hijiri Hasegawa et al.
SENSORS (2008)
Multidomain targeting generates a high-affinity thrombin-inhibiting bivalent aptamer
Jens Mueller et al.
CHEMBIOCHEM (2007)
G-quadruplex induced stabilization by 2'-deoxy-2'-fluoro-D-arabinonucleic acids (2'F-ANA)
Chang Geng Peng et al.
NUCLEIC ACIDS RESEARCH (2007)
Destabilization of quadruplex DNA by 8-aminoguanine
JP de la Osa et al.
CHEMBIOCHEM (2006)
Nucleic acid-based fluorescence sensors for detecting proteins
E Heyduk et al.
ANALYTICAL CHEMISTRY (2005)
The effect of chemical modifications on the thermal stability of different G-quadruplex-forming oligonucleotides
B Sacca et al.
NUCLEIC ACIDS RESEARCH (2005)
A novel method of screening thrombin-inhibiting DNA aptamers using an evolution-mimicking algorithm
K Ikebukuro et al.
NUCLEIC ACIDS RESEARCH (2005)
Construction, stability, and activity of multivalent circular anticoagulant aptamers
DA Di Giusto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)