相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。PPARγ enhanced Adiponectin polymerization and trafficking by promoting RUVBL2 expression during adipogenic differentiation
Daiyun Zhu et al.
GENE (2021)
PPARγ and Diabetes: Beyond the Genome and Towards Personalized Medicine
Simona Cataldi et al.
CURRENT DIABETES REPORTS (2021)
Leptin, Acting at Central Level, Increases FGF21 Expression in White Adipose Tissue via PPARβ/δ
Lorena Mazuecos et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Diet-dependent natriuretic peptide receptor C expression in adipose tissue is mediated by PPARγ via long-range distal enhancers
Fubiao Shi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2021)
PPAR-α activation counters brown adipose tissue whitening: a comparative study between high-fat- and high-fructose-fed mice
Carolline Santos Miranda et al.
NUTRITION (2020)
Shared PPARα/γ Target Genes Regulate Brown Adipocyte Thermogenic Function
Yachen Shen et al.
CELL REPORTS (2020)
Thermogenesis in Adipose Tissue Activated by Thyroid Hormone
Winifred W. Yau et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
TGF-β is insufficient to induce adipocyte state loss without concurrent PPARγ downregulation
Brooks Taylor et al.
SCIENTIFIC REPORTS (2020)
Adipose Tissue Distribution, Inflammation and Its Metabolic Consequences, Including Diabetes and Cardiovascular Disease
Alan Chait et al.
FRONTIERS IN CARDIOVASCULAR MEDICINE (2020)
Transcriptional and Epigenomic Regulation of Adipogenesis
Ji-Eun Lee et al.
MOLECULAR AND CELLULAR BIOLOGY (2019)
Feedback regulation of Arid5a and Ppar-γ2 maintains adipose tissue homeostasis
Jaya Prakash Chalise et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
The role of Ap2a2 in PPARα-mediated regulation of lipolysis in adipose tissue
Magdalene K. Montgomery et al.
FASEB JOURNAL (2019)
Altered adipose tissue and adipocyte function in the pathogenesis of metabolic syndrome
C. Ronald Kahn et al.
JOURNAL OF CLINICAL INVESTIGATION (2019)
What lipodystrophies teach us about the metabolic syndrome
Jake P. Mann et al.
JOURNAL OF CLINICAL INVESTIGATION (2019)
The E3 ligase MARCH5 is a PPARγ target gene that regulates mitochondria and metabolism in adipocytes
Simon T. Bond et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2019)
A role of peroxisome proliferator-activated receptor γ in non-alcoholic fatty liver disease
Josephine Skat-Rordam et al.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2019)
Adipogenesis and metabolic health
Alexandra L. Ghaben et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)
Ablation of PPARγ in subcutaneous fat exacerbates age-associated obesity and metabolic decline
Lingyan Xu et al.
AGING CELL (2018)
Functional Regulation of PPARs through Post-Translational Modifications
Reinhard Brunmeir et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
PPAR gamma deacetylation dissociates thiazolidinedione's metabolic benefits from its adverse effects
Michael J. Kraakman et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Heterogeneity of adipose tissue in development and metabolic function
Theresa Schoettl et al.
JOURNAL OF EXPERIMENTAL BIOLOGY (2018)
PPAR gamma agonist rosiglitazone switches fuel preference to lipids in promoting thermogenesis under cold exposure in C57BL/6 mice
Rong Gao et al.
JOURNAL OF PROTEOMICS (2018)
A truncated PPAR gamma 2 localizes to mitochondria and regulates mitochondrial respiration in brown adipocytes
Ji Suk Chang et al.
PLOS ONE (2018)
A noncanonical PPARγ/RXRα-binding sequence regulates leptin expression in response to changes in adipose tissue mass
Yinxin Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Peroxisome Proliferator Activated Receptor Gamma Controls Mature Brown Adipocyte Inducibility through Glycerol Kinase
David Lasar et al.
CELL REPORTS (2018)
The Peroxisome Proliferator-Activated Receptor alpha is dispensable for cold-induced adipose tissue browning in mice
Merel Defour et al.
MOLECULAR METABOLISM (2018)
PPARs and Metabolic Disorders Associated with Challenged Adipose Tissue Plasticity
Patricia Corrales et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
The roles of PPARs in human diseases
Jingjing Li et al.
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS (2018)
Peroxisome Proliferator-Activated Receptor γ2 Controls the Rate of Adipose Tissue Lipid Storage and Determines Metabolic Flexibility
Sam Virtue et al.
CELL REPORTS (2018)
Benefits and risks of the treatment with fibrates--a comprehensive summary
Boguslaw Okopien et al.
EXPERT REVIEW OF CLINICAL PHARMACOLOGY (2018)
Impact of fat mass and distribution on lipid turnover in human adipose tissue
Kirsty L. Spalding et al.
NATURE COMMUNICATIONS (2017)
Human brown adipose tissue - function and therapeutic potential in metabolic disease
Padmanabh Shrikant Bhatt et al.
CURRENT OPINION IN PHARMACOLOGY (2017)
Regulation of lipid droplet-associated proteins by peroxisome proliferator-activated receptors
Montserrat A. de la Rosa Rodriguez et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2017)
Browning of White Adipose Tissue with Roscovitine Induces a Distinct Population of UCP1+ Adipocytes
Hong Wang et al.
Cell Metabolism (2016)
Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD
Alexandra Montagner et al.
GUT (2016)
Adiponectin reduces ER stress-induced apoptosis through PPARα transcriptional regulation of ATF2 in mouse adipose
Zhenjiang Liu et al.
CELL DEATH & DISEASE (2016)
White-to-brite conversion in human adipocytes promotes metabolic reprogramming towards fatty acid anabolic and catabolic pathways
V. Barquissau et al.
MOLECULAR METABOLISM (2016)
Brown adipose tissue: physiological function and evolutionary significance
R. Oelkrug et al.
JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMS AND ENVIRONMENTAL PHYSIOLOGY (2015)
Fenofibrate (PPARalpha agonist) induces beige cell formation in subcutaneous white adipose tissue from diet-induced male obese mice
Tamiris Lima Rachid et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2015)
Activation of Classical Brown Adipocytes in the Adult Human Perirenal Depot Is Highly Correlated with PRDM16-EHMT1 Complex Expression
Gaku Nagano et al.
PLOS ONE (2015)
Browning of human adipocytes requires KLF11 and reprogramming of PPAR gamma superenhancers
Anne Loft et al.
GENES & DEVELOPMENT (2015)
PPARδ binding to heme oxygenase 1 promoter prevents angiotensin II-induced adipocyte dysfunction in Goldblatt hypertensive rats
K. Sodhi et al.
INTERNATIONAL JOURNAL OF OBESITY (2014)
Adipose tissue browning and metabolic health
Alexander Bartelt et al.
NATURE REVIEWS ENDOCRINOLOGY (2014)
EBF2 Determines and Maintains Brown Adipocyte Identity
Sona Rajakumari et al.
CELL METABOLISM (2013)
PPARα agonist fenofibrate attenuates TNF-α-induced CD40 expression in 3T3-L1 adipocytes via the SIRT1-dependent signaling pathway
Weirong Wang et al.
EXPERIMENTAL CELL RESEARCH (2013)
PPARγ signaling and metabolism: the good, the bad and the future
Maryam Ahmadian et al.
NATURE MEDICINE (2013)
Lipoatrophy and severe metabolic disturbance in mice with fat-specific deletion of PPARγ
Fenfen Wang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Nuclear receptor-mediated regulation of lipid droplet-associated protein gene expression in adipose tissue
Mark Christian
HORMONE MOLECULAR BIOLOGY AND CLINICAL INVESTIGATION (2013)
Brown Remodeling of White Adipose Tissue by SirT1-Dependent Deacetylation of Pparγ
Li Qiang et al.
CELL (2012)
Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human
Jun Wu et al.
CELL (2012)
PPARγ agonists Induce a White-to-Brown Fat Conversion through Stabilization of PRDM16 Protein
Haruya Ohno et al.
CELL METABOLISM (2012)
Activation of peroxisome proliferator-activated receptor-α enhances fatty acid oxidation in human adipocytes
Joo-Young Lee et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Activation of Peroxisome Proliferator-Activated Receptor-β/-δ (PPAR-β/-δ) Ameliorates Insulin Signaling and Reduces SOCS3 Levels by Inhibiting STAT3 in Interleuldn-6 Stimulated Adipocytes
Lucia Serrano-Marco et al.
DIABETES (2011)
Peroxisome Proliferator-activated Receptor α (PPARα) Induces PPARγ Coactivator 1α (PGC-1α) Gene Expression and Contributes to Thermogenic Activation of Brown Fat INVOLVEMENT OF PRDM16
Elayne Hondares et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
cis-9,trans-11,cis-15 and cis-9,trans-13,cis-15 CLNA Mixture Activates PPARα in HEK293 and Reduces Triacylglycerols in 3T3-L1 cells
Jonatan Miranda et al.
LIPIDS (2011)
Control of Brown Adipose Tissue Glucose and Lipid Metabolism by PPARγ
William T. Festuccia et al.
Frontiers in Endocrinology (2011)
Basal adrenergic tone is required for maximal stimulation of rat brown adipose tissue UCP1 expression by chronic PPAR-γ activation
William T. Festuccia et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2010)
Multiple roles of PPARα in brown adipose tissue under constitutive and cold conditions
Makiko Komatsu et al.
GENES TO CELLS (2010)
Chronic Peroxisome Proliferator-activated Receptor γ (PPARγ) Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct from Classic Brown Adipocytes
Natasa Petrovic et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
The PPARγ agonist rosiglitazone enhances rat brown adipose tissue lipogenesis from glucose without altering glucose uptake
William T. Festuccia et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2009)
Tissue-specific postprandial clearance is the major determinant of PPAR gamma-induced triglyceride lowering in the rat
Mathieu Laplante et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2009)
Twist-1 Is a PPARδ-Inducible, Negative-Feedback Regulator of PGC-1α in Brown Fat Metabolism
Dongning Pan et al.
CELL (2009)
Depot specificities of PPAR gamma ligand actions on lipid and glucose metabolism and their implication in PPAR gamma-mediated body fat redistribution
William T. Festuccia et al.
CLINICAL LIPIDOLOGY (2009)
C/EBP alpha and the Corepressors CtBP1 and CtBP2 Regulate Repression of Select Visceral White Adipose Genes during Induction of the Brown Phenotype in White Adipocytes by Peroxisome Proliferator-Activated Receptor gamma Agonists
Cecile Vernochet et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Thermogenically competent nonadrenergic recruitment in brown preadipocytes by a PPARγ agonist
Natasa Petrovic et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2008)
Fat and beyond: The diverse biology of PPAR gamma
Peter Tontonoz et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2008)
Adipocyte-derived Th2 cytokines and myeloid PPARδ regulate macrophage polarization and insulin sensitivity
Kihwa Kang et al.
CELL METABOLISM (2008)
Peroxisome proliferator-activated receptor-γ-mediated positive energy balance in the rat is associated with reduced sympathetic drive to adipose tissues and thyroid status
William T. Festuccia et al.
ENDOCRINOLOGY (2008)
PPARγ and C/EBP factors orchestrate adipocyte biology via adjacent binding on a genome-wide scale
Martina I. Lefterova et al.
GENES & DEVELOPMENT (2008)
Adipose fibroblast growth factor 21 is up-regulated by peroxisome proliferator-activated receptor γ and altered metabolic states
Eric S. Muise et al.
MOLECULAR PHARMACOLOGY (2008)
Influence of obesity and insulin sensitivity on insulin signaling genes in human omental and subcutaneous adipose tissue
R. MacLaren et al.
JOURNAL OF LIPID RESEARCH (2008)
The transcriptional coactivator peroxisome proliferator-activated receptor (PPAR)γ coactivator-1α and the nuclear receptor PPARα control the expression of glycerol kinase and metabolism genes independently of PPARγ activation in human white adipocytes
Anne Mazzucotelli et al.
DIABETES (2007)
PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism
Gema Medina-Gomez et al.
PLOS GENETICS (2007)
PPARγ agonism increases rat adipose tissue lipolysis, expression of glyceride lipases, and the response of lipolysis to hormonal control
W. T. Festuccia et al.
DIABETOLOGIA (2006)
PPARγ and human metabolic disease
RK Semple et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Peroxisome proliferator-activated receptor (PPAR)α activation increases adiponectin receptors and reduces obesity-related inflammation in adipose tissue -: Comparison of activation of PPARα, PPAR-γ, and their combination
A Tsuchida et al.
DIABETES (2005)
Suppression of expression of muscle-associated proteins by PPARα in brown adipose tissue
YH Tong et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Peroxisome proliferator-activated receptor β/δ as a therapeutic target for metabolic diseases
E Bedu et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2005)
Deletion of PPARγ in adipose tissues of mice protects against high fat diet-induced obesity and insulin resistance
JR Jones et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Brown adipose tissue glyceroneogenesis is activated in rats exposed to cold
MAF Moura et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2005)
Peroxisome proliferator-activated receptor γ is required in mature white and brown adipocytes for their survival in the mouse
T Imai et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Noradrenaline represses PPAR (peroxisome-proliferator-activated receptor) γ2 gene expression in brown adipocytes:: intracellular signalling and effects on PPAγ2 and PPARγ1 orotein levels
EM Lindgren et al.
BIOCHEMICAL JOURNAL (2004)
Adipose-specific peroxisome proliferator-activated receptor γ knockout causes insulin resistance in fat and liver but not in muscle
WM He et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Peroxisome-proliferator-activated receptor δ activates fat metabolism to prevent obesity
YX Wang et al.
CELL (2003)
PPAR gamma knockdown by engineered transcription factors: exogenous PPAR gamma 2 but not PPAR gamma 1 reactivates adipogenesis
DL Ren et al.
GENES & DEVELOPMENT (2002)
Mechanisms by which both heterozygous peroxisome proliferator-activated receptor γ (PPARγ) deficiency and PPARγ agonist improve insulin resistance.
T Yamauchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
C/EBPα is required for differentiation of white, but not brown, adipose tissue
HG Linhart et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Peroxisome proliferator-activated receptor δ (PPhRδ)-mediated regulation of preadipocyte proliferation and gene expression is dependent on cAMP signaling
JB Hansen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Regulation of adipogenesis and energy balance by PPARγ and PGC-1
BM Spiegelman et al.
INTERNATIONAL JOURNAL OF OBESITY (2000)
Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor β(δ)
JM Peters et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)