相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Discovery and Preclinical Development of Orally Active Small Molecules that Exhibit Highly Selective Follicle Stimulating Hormone Receptor Agonism
Selva Nataraja et al.
FRONTIERS IN PHARMACOLOGY (2021)
Pharmacological Programming of Endosomal Signaling Activated by Small Molecule Ligands of the Follicle Stimulating Hormone Receptor
Silvia Sposini et al.
FRONTIERS IN PHARMACOLOGY (2020)
Biased Signaling and Allosteric Modulation at the FSHR
Flavie Landomiel et al.
FRONTIERS IN ENDOCRINOLOGY (2019)
Variable G protein determinants of GPCR coupling selectivity
Najeah Okashah et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Small Molecule Follicle-Stimulating Hormone Receptor Agonists and Antagonists
Ross C. Anderson et al.
FRONTIERS IN ENDOCRINOLOGY (2019)
The hypothalamus-pituitary-gonad axis: Tales of mice and men
Athina Kaprara et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2018)
G protein-dependent signaling triggers a β-arrestin-scaffolded p70S6K/rpS6 module that controls 5′TOP mRNA translation
Aurelie Trefier et al.
FASEB JOURNAL (2018)
Mini G protein probes for active G protein-coupled receptors (GPCRs) in live cells
Qingwen Wan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Kinetic operational models of agonism for G-protein-coupled receptors
Samuel R. J. Hoare et al.
JOURNAL OF THEORETICAL BIOLOGY (2018)
Biased signalling: from simple switches to allosteric microprocessors
Jeffrey S. Smith et al.
NATURE REVIEWS DRUG DISCOVERY (2018)
Lack of beta-arrestin signaling in the absence of active G proteins
Manuel Grundmann et al.
NATURE COMMUNICATIONS (2018)
Manifold roles of beta-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9
Louis M. Luttrell et al.
SCIENCE SIGNALING (2018)
Allosteric Regulation of the Follicle-Stimulating Hormone Receptor
Selvaraj Nataraja et al.
ENDOCRINOLOGY (2018)
FSH Receptor Signaling: Complexity of Interactions and Signal Diversity
Alfredo Ulloa-Aguirre et al.
ENDOCRINOLOGY (2018)
Purinergic Receptor Transactivation by the β2-Adrenergic Receptor Increases Intracellular Ca2+ in Nonexcitable Cells
Wayne Stallaert et al.
MOLECULAR PHARMACOLOGY (2017)
Genetic evidence that β-arrestins are dispensable for the initiation of β2-adrenergic receptor signaling to ERK
Morgan O'Hayre et al.
SCIENCE SIGNALING (2017)
Integration of GPCR Signaling and Sorting from Very Early Endosomes via Opposing APPL1 Mechanisms
Silvia Sposini et al.
CELL REPORTS (2017)
Genetic evidence that β-arrestins are dispensable for the initiation of β2-adrenergic receptor signaling to ERK
Morgan O'Hayre et al.
SCIENCE SIGNALING (2017)
Genetics of gonadotropins and their receptors as markers of ovarian reserve and response in controlled ovarian stimulation
Laura Riccetti et al.
BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY (2017)
Allosteric Modulation as a Unifying Mechanism for Receptor Function and Regulation
Jean-Pierre Changeux et al.
CELL (2016)
The role of kinetic context in apparent biased agonism at GPCRs
Carmen Klein Herenbrink et al.
NATURE COMMUNICATIONS (2016)
Data2Dynamics: a modeling environment tailored to parameter estimation in dynamical systems
A. Raue et al.
BIOINFORMATICS (2015)
Assessing gonadotropin receptor function by resonance energy transfer-based assays
Mohammed Akli Ayoub et al.
FRONTIERS IN ENDOCRINOLOGY (2015)
Discovery and development of small molecule allosteric modulators of glycoprotein hormone receptors
Selvaraj G. Nataraja et al.
FRONTIERS IN ENDOCRINOLOGY (2015)
A Novel Method for Analyzing Extremely Biased Agonism at G Protein-Coupled Receptors
Edward L. Stahl et al.
MOLECULAR PHARMACOLOGY (2015)
Investigation of a thiazolidinone derivative as an allosteric modulator of follicle stimulating hormone receptor: Evidence for its ability to support follicular development and ovulation
Venkataraman Sriraman et al.
BIOCHEMICAL PHARMACOLOGY (2014)
Comparison of approaches for parameter identifiability analysis of biological systems
Andreas Raue et al.
BIOINFORMATICS (2014)
Discovery of substituted benzamides as follicle stimulating hormone receptor allosteric modulators
Henry N. Yu et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2014)
Quantification of Ligand Bias for Clinically Relevant β2-Adrenergic Receptor Ligands: Implications for Drug Taxonomy
Emma T. van der Westhuizen et al.
MOLECULAR PHARMACOLOGY (2014)
Signaling of an allosteric, nanomolar potent, low molecular weight agonist for the follicle-stimulating hormone receptor
Chris J. van Koppen et al.
BIOCHEMICAL PHARMACOLOGY (2013)
The Dynamic Process of β2-Adrenergic Receptor Activation
Rie Nygaard et al.
CELL (2013)
Emerging paradigms in GPCR allostery: implications for drug discovery
Denise Wootten et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
Structural Features for Functional Selectivity at Serotonin Receptors
Daniel Wacker et al.
SCIENCE (2013)
A Simple Method for Quantifying Functional Selectivity and Agonist Bias
Terry Kenakin et al.
ACS CHEMICAL NEUROSCIENCE (2012)
Molecular Mechanism of beta-Arrestin-Biased Agonism at Seven-Transmembrane Receptors
Eric Reiter et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 52 (2012)
Preferential beta-arrestin signalling at low receptor density revealed by functional characterization of the human FSH receptor A189 V mutation
Thibaud Tranchant et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2011)
Quantifying Ligand Bias at Seven-Transmembrane Receptors
Sudarshan Rajagopal et al.
MOLECULAR PHARMACOLOGY (2011)
Structural insights into adrenergic receptor function and pharmacology
Brian K. Kobilka
TRENDS IN PHARMACOLOGICAL SCIENCES (2011)
β-arrestin-biased ligands at seven-transmembrane receptors
Jonathan D. Violin et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2007)
The evasive nature of drug efficacy:: implications for drug discovery
Segolene Galandrin et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2007)
Use of a cAMP BRET sensor to characterize a novel regulation of cAMP by the sphingosine 1-phosphate/G13 pathway
Lily I. Jiang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
A phosphorylation cluster of five serine and threonine residues in the C-terminus of the follicle-stimulating hormone receptor is important for desensitization but not for β-arrestin-mediated ERK activation
Elodie Kara et al.
MOLECULAR ENDOCRINOLOGY (2006)
Follicle-stimulating hormone (FSH) activates extracellular signal-regulated kinase phosphorylation independently of beta-arrestin- and dynamin-mediated FSH receptor internalization
Vincent Piketty et al.
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY (2006)
Structure of human follicle-stimulating hormone in complex with its receptor
QR Fan et al.
NATURE (2005)
Ligand-selective receptor conformations revisited: the promise and the problem
T Kenakin
TRENDS IN PHARMACOLOGICAL SCIENCES (2003)
Follicle-stimulating hormone activates extracellular signal-regulated kinase but not extracellular signal-regulated kinase kinase through a 100-kDa phosphotyrosine phosphatase
J Cottom et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Protein kinase A-mediated phosphorylation of the β2-Adrenergic receptor regulates its coupling to Gs and Gi -: Demonstration in a reconstituted system
AM Zamah et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Follicle-stimulating hormone stimulates protein kinase A-mediated histone H3 phosphorylation and acetylation leading to select gene activation in ovarian granulosa cells
LM Salvador et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
The ERK-dependent signalling is stage-specifically modulated by FSH, during primary Sertoli cell maturation
P Crépieux et al.
ONCOGENE (2001)
分享论文
