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Activation of the Hedgehog Signaling Pathway in the Developing Lens Stimulates Ectopic FoxE3 Expression and Disruption in Fiber Cell Differentiation
Christine L. Kerr et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2012)
The Wnt Signaling Pathway Protects Retinal Ganglion Cell 5 (RGC-5) Cells from Elevated Pressure
Miryam A. Fragoso et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2011)
The specificities of small molecule inhibitors of the TGFβ and BMP pathways
Janis Vogt et al.
CELLULAR SIGNALLING (2011)
Chemical 'Jekyll and Hyde's: small-molecule inhibitors of developmental signaling pathways
Tomoyo Sakata et al.
CHEMICAL SOCIETY REVIEWS (2011)
BMP signaling orchestrates photoreceptor specification in the zebrafish pineal gland in collaboration with Notch
Aurelie Quillien et al.
DEVELOPMENT (2011)
Regulation of NMDA-Receptor Synaptic Transmission by Wnt Signaling
Waldo Cerpa et al.
JOURNAL OF NEUROSCIENCE (2011)
Small-Molecule Inhibitors of Bone Morphogenic Protein and Activin/Nodal Signals Promote Highly Efficient Neural Induction From Human Pluripotent Stem Cells
Asuka Morizane et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2011)
Self-organizing optic-cup morphogenesis in three-dimensional culture
Mototsugu Eiraku et al.
NATURE (2011)
Wnt signaling and a Smad pathway blockade direct the differentiation of human pluripotent stem cells to multipotent neural crest cells
Laura Menendez et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Optic Vesicle-like Structures Derived from Human Pluripotent Stem Cells Facilitate a Customized Approach to Retinal Disease Treatment
Jason S. Meyer et al.
STEM CELLS (2011)
Planar cell polarity in the mammalian eye lens
Yuki Sugiyama et al.
ORGANOGENESIS (2011)
Smad4 Is Required Predominantly in the Developmental Processes Dependent on the BMP Branch of the TGF-β Signaling System in the Embryonic Mouse Retina
Deepa Murali et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2011)
The Nodal Inhibitor Coco Is a Critical Target of Leftward Flow in Xenopus
Axel Schweickert et al.
CURRENT BIOLOGY (2010)
Dorsomorphin and LDN-193189 inhibit BMP-mediated Smad, p38 and Akt signalling in C2C12 cells
J. H. Boergermann et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2010)
Neuroretina specification in mouse embryos requires S1x3-mediated suppression of Wnt8b in the anterior neural plate
Wei Liu et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Small-molecule modulators of the Sonic Hedgehog signaling pathway
Benjamin Z. Stanton et al.
MOLECULAR BIOSYSTEMS (2010)
Generation, Purification and Transplantation of Photoreceptors Derived from Human Induced Pluripotent Stem Cells
Deepak A. Lamba et al.
PLOS ONE (2010)
Robust Enhancement of Neural Differentiation from Human ES and iPS Cells Regardless of their Innate Difference in Differentiation Propensity
Dae-Sung Kim et al.
STEM CELL REVIEWS AND REPORTS (2010)
Building the developmental oculome: systems biology in vertebrate eye development and disease
Salil A. Lachke et al.
WILEY INTERDISCIPLINARY REVIEWS-SYSTEMS BIOLOGY AND MEDICINE (2010)
Regulation of Retinal Progenitor Cell Differentiation by Bone Morphogenetic Protein 4 Is Mediated by the Smad/Id Cascade
Yang Du et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2010)
TGFβ family signaling: novel insights in development and disease
Kristi Wharton et al.
DEVELOPMENT (2009)
Metalloprotease ADAM10 Is Required for Notch1 Site 2 Cleavage
Geert van Tetering et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling
Stuart M. Chambers et al.
NATURE BIOTECHNOLOGY (2009)
Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer
Baozhi Chen et al.
NATURE CHEMICAL BIOLOGY (2009)
Modeling early retinal development with human embryonic and induced pluripotent stem cells
Jason S. Meyer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Structure of cone photoreceptors
Debarshi Mustafi et al.
PROGRESS IN RETINAL AND EYE RESEARCH (2009)
Structure-activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors
Gregory D. Cuny et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
An essential role for frizzled 5 in mammalian ocular development
Chunqiao Liu et al.
DEVELOPMENT (2008)
Indian hedgehog signaling from endothelial cells is required for sclera and retinal pigment epithelium development in the mouse eye
Gabriel D. Dakubo et al.
DEVELOPMENTAL BIOLOGY (2008)
The role of kinases in the Hedgehog signalling pathway
Reid A. Aikin et al.
EMBO REPORTS (2008)
Heparin activates Wnt signaling for neuronal morphogenesis
Marcela Colombres et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2008)
Heparin promotes the growth of human embryonic stem cells in a defined serum-free medium
Miho K. Furue et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism
Paul B. Yui et al.
NATURE CHEMICAL BIOLOGY (2008)
Differential, age-dependent MEK-ERK and PI3K-Akt activation by insulin acting as a survival factor during embryonic retinal development
Teresa Chavarria et al.
DEVELOPMENTAL NEUROBIOLOGY (2007)
Transient inactivation of Notch signaling synchronizes differentiation of neural progenitor cells
Branden R. Nelson et al.
DEVELOPMENTAL BIOLOGY (2007)
Notch signaling is essential for ventricular chamber development
Joaquin Grego-Bessa et al.
DEVELOPMENTAL CELL (2007)
Notch activity permits retinal cells to progress through multiple progenitor states and acquire a stem cell property
Ashutosh P. Jadhav et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Efficient generation of retinal progenitor cells from human embryonic stem cells
Deepak A. Lamba et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Notch 1 inhibits photoreceptor production in the developing mammalian retina
AR Jadhav et al.
DEVELOPMENT (2006)
Inhibition of GLI1 gene activation by patched1
F Rahnama et al.
BIOCHEMICAL JOURNAL (2006)
Notch activity is downregulated just prior to retinal ganglion cell differentiation
BR Nelson et al.
DEVELOPMENTAL NEUROSCIENCE (2006)
One-step induction of neurons from mouse embryonic stem cells in serum-free media containing vitamin B-12 and heparin
Hironori Yamazoe et al.
CELL TRANSPLANTATION (2006)
Fate maps of neural crest and mesoderm in the mammalian eye
PJ Gage et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)
Crooked tail (Cd) model of human folate-responsive neural tube defects is mutated in Wnt coreceptor lipoprotein receptor-related protein 6
M Carter et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Early stages of zebrafish eye formation require the coordinated activity of Wnt11, Fz5, and the Wnt/β-catenin pathway
F Cavodeassi et al.
NEURON (2005)
GDF11 controls the timing of progenitor cell competence in developing retina
J Kim et al.
SCIENCE (2005)
WNTs in the vertebrate nervous system: From patterning to neuronal connectivity
L Ciani et al.
NATURE REVIEWS NEUROSCIENCE (2005)
SB-505124 is a selective inhibitor of transforming growth factor-β type I receptors ALK4, ALK5, and ALK7
SD Byfield et al.
MOLECULAR PHARMACOLOGY (2004)
Coordinate regulation of neural tube patterning and proliferation by TGFβ and WNT activity
C Chesnutt et al.
DEVELOPMENTAL BIOLOGY (2004)
Notch signaling controls multiple steps of pancreatic differentiation
LC Murtaugh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
The roles of Hedgehogs and Fibroblast Growth Factors in eye development and retinal cell rescue
C Russell
VISION RESEARCH (2003)
Regulation of ganglion cell production by notch signaling during retinal development
AO Silva et al.
JOURNAL OF NEUROBIOLOGY (2003)
The stability of the lens-specific maf protein is regulated by fibroblast growth factor (FGF)/ERK signaling in lens fiber differentiation
H Ochi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
SB-431542 is a potent and specific inhibitor of transforming growth factor-β superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7
GJ Inman et al.
MOLECULAR PHARMACOLOGY (2002)
Hedgehog patterns midbrain ARChitecture
R Machold et al.
TRENDS IN NEUROSCIENCES (2002)
Hedgehog signaling in animal development: paradigms and principles
PW Ingham et al.
GENES & DEVELOPMENT (2001)
Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6
MV Semënov et al.
CURRENT BIOLOGY (2001)
Regulation of eye development by frizzled signaling in Xenopus
JT Rasmussen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Patterning of the zebrafish retina by a wave of sonic hedgehog activity
CJ Neumann et al.
SCIENCE (2000)
Function for hedgehog genes in zebrafish retinal development
DL Stenkamp et al.
DEVELOPMENTAL BIOLOGY (2000)
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