期刊
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
卷 22, 期 11, 页码 -出版社
MDPI
DOI: 10.3390/ijms22115746
关键词
fermented soybean paste; cheonggukjang; bioactive molecule; biological activity; human health benefit
资金
- National Research Foundation of Korea [NRF-2019R1I1A1A01058109]
- Korea Institute of Planning and Evaluation for Technology in Food, Agriculture and Forestry [IPET 119010033SB010, 119010033CG000]
Cheonggukjang, a traditional Korean fermented dish, has emerged as a functional food with various health benefits, such as improving blood circulation and intestinal regulation. It is made without salt and contains bioactive substances that prevent atherosclerosis, heart disease, inflammation, obesity, diabetes, dementia, cancer, and osteoporosis, among other health conditions. Studies have shown that Cheonggukjang also has thrombolytic, blood pressure-lowering, lipid-lowering, antimutagenic, immunostimulatory, and antibacterial properties, as well as skin improvement benefits.
Cheonggukjang (CGJ, fermented soybean paste), a traditional Korean fermented dish, has recently emerged as a functional food that improves blood circulation and intestinal regulation. Considering that excessive consumption of refined salt is associated with increased incidence of gastric cancer, high blood pressure, and stroke in Koreans, consuming CGJ may be desirable, as it can be made without salt, unlike other pastes. Soybeans in CGJ are fermented by Bacillus strains (B. subtilis or B. licheniformis), Lactobacillus spp., Leuconostoc spp., and Enterococcus faecium, which weaken the activity of putrefactive bacteria in the intestines, act as antibacterial agents against pathogens, and facilitate the excretion of harmful substances. Studies on CGJ have either focused on improving product quality or evaluating the bioactive substances contained in CGJ. The fermentation process of CGJ results in the production of enzymes and various physiologically active substances that are not found in raw soybeans, including dietary fiber, phospholipids, isoflavones (e.g., genistein and daidzein), phenolic acids, saponins, trypsin inhibitors, and phytic acids. These components prevent atherosclerosis, oxidative stress-mediated heart disease and inflammation, obesity, diabetes, senile dementia, cancer (e.g., breast and lung), and osteoporosis. They have also been shown to have thrombolytic, blood pressure-lowering, lipid-lowering, antimutagenic, immunostimulatory, anti-allergic, antibacterial, anti-atopic dermatitis, anti-androgenetic alopecia, and anti-asthmatic activities, as well as skin improvement properties. In this review, we examined the physiological activities of CGJ and confirmed its potential as a functional food.
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