4.4 Article

Key genetic and forensic attributes of Uttarakhand population of India

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INTERNATIONAL JOURNAL OF LEGAL MEDICINE
卷 135, 期 6, 页码 2311-2314

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SPRINGER
DOI: 10.1007/s00414-021-02637-5

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PowerPlex (R) 21 System; Uttarakhand; Genetic diversity; Forensic parameters

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The study investigated the genetic and forensic attributes of the Uttarakhand population using 20 autosomal STR loci in the PowerPlex (R) 21 System. Results revealed Penta E locus as the most polymorphic and discriminative, with higher heterozygosity within the population. Phylogenetic analysis showed a higher genetic affinity of the Uttarakhand population with the neighboring Himachal Pradesh population.
The present study aimed to investigate the genetic and forensic attributes of Uttarakhand population based on 20 autosomal STR loci implemented in PowerPlex (R) 21 System. Results unveiled 219 alleles ranging from 6 (TH01, TPOX) to 20 (Penta E). Forensic analysis revealed locus Penta E as the most polymorphic and discriminative loci, whereas genetic analysis indicated presence of higher heterozygosity within population. Phylogenetic analysis indicated higher genetic affinity of Uttarakhand population with the neighbouring Himachal Pradesh population. Overall, the study indicates that the PowerPlex (R) 21 System is suitable for genetic and forensic analysis in Uttarakhand population.

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