Recent advances in PVA-polysaccharide based hydrogels and electrospun nanofibers in biomedical applications: A review

Among several types of carbohydrate polymers blend PVA hydrogel membranes used for biomedical applications in particular wound dressings; electrospun nanofibrous membranes have gained increased interest because of their extraordinary features e.g. huge surface area to volume ratio, high porosity, adequate permeability, excellent wound-exudates absorption capacity, architecture similarity with skin ECM and sustained releaseprofile over long time. In this study, modern perspectives of synthesized/developed electrospun nanofibrous hydrogel membranes based popular carbohydrate polymers blend PVA which recently have been employed for versatile biomedical applications particularly wound dressings, were discussed intensively and compared in detail with traditional fabricated membranes based films, as well. Clinically relevant and advantages of electrospun nanofibrous membranes were discussed in terms of their biocompatibility and easily fabrication and functionalization in different biomedical applications.

Automated summary

This study extensively discussed the modern perspectives of synthesized/developed electrospun nanofibrous hydrogel membranes based on popular carbohydrate polymers blend PVA, which have been widely used in versatile biomedical applications, particularly wound dressings, and compared them in detail with traditional fabricated membranes based films. The clinically relevant advantages of electrospun nanofibrous membranes were highlighted in terms of their biocompatibility, easy fabrication, and functionalization for different biomedical applications.