期刊
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
卷 183, 期 -, 页码 1971-1977出版社
ELSEVIER
DOI: 10.1016/j.ijbiomac.2021.05.162
关键词
Chitosan; Carboxymethyl chitosan; Microorganisms
资金
- Tertiary Education Trust Fund (TETFUND)
- Ekiti State University, Nigeria
The study focused on the preparation and antibacterial evaluation of chitosan, carboxymethyl chitosan, and their respective metal composites. The results showed that carboxymethyl chitosan and its metal composites performed better at inhibiting microbial growth than chitosan and its metal composites, as revealed by SEM, EDS, and XRD analysis.
The study focused on the preparation and antibacterial evaluation of chitosan (CHT), carboxymethyl chitosan (CMC) and their respective metal composites. All the samples were characterized using Fourier Transform Infrared (FTIR), scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDS) and X-ray diffraction (XRD). The antibacterial potentials of the samples were tested against Escherichia coli, Klebsiella sp., Pseudomonas aeruginosa A, and Pseudomonas aeruginosa B. SEM results revealed different changes in samples surfaces as a result of chemical modification. EDS revealed the presence of Ni and Cu in the composites. XRD spectra of CMC showed that the crystalline region of CHT was reduced by the modification. The antibacterial results indicated that the samples had inhibitory and bactericidal effects against Escherichia coli and Klebsiella sp. at 1000, 500, and 250 mg mL-1. The study showed that CMC and CMC-metal composites performed better at inhibiting the growth of microorganisms than CHT and CHT-metal composites.
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