期刊
INFLAMMATORY BOWEL DISEASES
卷 28, 期 3, 页码 486-491出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/ibd/izab183
关键词
aeroallergens; atopic disease; seasonality; environmental factors; inflammatory bowel disease; crohn's disease; ulcerative colitis
资金
- Bingham Chair in Gastroenterology
Inflammatory bowel diseases (IBD) are immune dysregulation disorders that are influenced by genetic predisposition and environmental factors. The role of aeroallergens in the pathogenesis of IBD has not been thoroughly investigated and requires further research.
Inflammatory bowel diseases (IBD) including Crohn's disease and ulcerative colitis are conditions characterized by immune dysregulation to a trigger in those with a genetic predisposition. Environmental factors are thought to contribute to IBD, but no definite trigger has been identified. Aeroallergens have not been thoroughly investigated in their potential contribution to the pathogenesis to IBD. The geographic distribution of aeroallergens and IBD, the association of atopic disease with IBD, seasonality and IBD, and cross-reactive food allergens require further study with implications for targeted dietary and immunomodulatory therapies.
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