Diagnosis and management of cardiac allograft vasculopathy

One of the main causes of death beyond the first year after heart transplantation is cardiac allograft vasculopathy (CAV). This review summarises the current understanding of its complex pathophysiology, detection and treatment, including the available data on non-invasive imaging modalities used for screening and diagnosis. A better understanding of this entity is crucial to improving the long-term outcomes of the growing population of patients with a heart transplant.

Automated summary

This review provides an overview of the complex pathophysiology, detection, and treatment of cardiac allograft vasculopathy (CAV) beyond the first year post heart transplantation. Understanding CAV is crucial for improving long-term outcomes in heart transplant patients.