4.8 Review

Faecal immunochemical tests safely enhance rational use of resources during the assessment of suspected symptomatic colorectal cancer in primary care: systematic review and meta-analysis

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Summary: The study indicated that the sensitivity of FIT is maximized at the lowest cut-off of 2 mu g/g, reaching 97.0%. A negative FIT result at this cut-off can effectively rule out CRC, while a positive FIT result is better than symptoms for selecting patients for urgent investigations.
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Diagnostic performance of a faecal immunochemical test for patients with low-risk symptoms of colorectal cancer in primary care: an evaluation in the South West of England

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Colorectal cancer incidence and mortality after negative fecal immunochemical tests by age 70: A prospective observational study

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