4.7 Article

Dehydroepiandrosterone alleviates intestinal inflammatory damage via GPR30-mediated Nrf2 activation and NLRP3 inflammasome inhibition in colitis mice

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Dehydroepiandrosterone attenuates LPS-induced inflammatory responses via activation of Nrf2 in RAW264.7 macrophages

Ji Cao et al.

Summary: DHEA suppresses inflammatory responses through the activation of Nrf2 and inhibition of NF-kappa B in LPS-stimulated macrophages.

MOLECULAR IMMUNOLOGY (2021)

Editorial Material Gastroenterology & Hepatology

The intestinal barrier, an arbitrator turned provocateur in IBD

Saurabh Mehandru et al.

Summary: Key studies in 2020 highlight that impaired intestinal barrier function precedes the clinical diagnosis of inflammatory bowel disease by years and could serve as a potential therapeutic target in the future.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2021)

Article Biochemistry & Molecular Biology

Reductively modified albumin attenuates DSS-Induced mouse colitis through rebalancing systemic redox state

Xiawen Yang et al.

Summary: The study demonstrates that r-Alb effectively alleviates DSS-induced colitis through ?SH group-mediated antioxidative action. Unmodified Alb has less impact in this aspect, while complete loss of efficacy is observed after removal of ?SH groups.

REDOX BIOLOGY (2021)

Article Endocrinology & Metabolism

Statins activate the NLRP3 inflammasome and impair insulin signaling via p38 and mTOR

Brandyn D. Henriksbo et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2020)

Article Biochemistry & Molecular Biology

Sleep Loss Can Cause Death through Accumulation of Reactive Oxygen Species in the Gut

Alexandra Vaccaro et al.

Article Biochemistry & Molecular Biology

SOD1 suppresses pro-inflammatory immune responses by protecting against oxidative stress in colitis

Jiyoung Hwang et al.

REDOX BIOLOGY (2020)

Review Medicine, General & Internal

Pathophysiology of Inflammatory Bowel Diseases

John T. Chang

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Review Gastroenterology & Hepatology

Control and dysregulation of redox signalling in the gastrointestinal tract

Eric L. Campbell et al.

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2019)

Article Multidisciplinary Sciences

Enhancement of the gut barrier integrity by a microbial metabolite through the Nrf2 pathway

Rajbir Singh et al.

NATURE COMMUNICATIONS (2019)

Editorial Material Medicine, General & Internal

Inflammatory Bowel Disease and the NLRP3 Inflammasome

Thirumala-Devi Kanneganti

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Biochemistry & Molecular Biology

Redox regulation of proteasome function

Maria Lefaki et al.

REDOX BIOLOGY (2017)

Article Gastroenterology & Hepatology

Tight junctions in inflammatory bowel diseases and inflammatory bowel disease associated colorectal cancer

Jonathan Landy et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2016)

Review Gastroenterology & Hepatology

Human Intestinal Barrier Function in Health and Disease

Julia Konig et al.

CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY (2016)

Review Biochemistry & Molecular Biology

The complexity of the Nrf2 pathway: beyond the antioxidant response

Ying Huang et al.

JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2015)

Article Biochemistry & Molecular Biology

Dehydroepiandrosterone: A neuroactive steroid

Luboslav Starka et al.

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2015)

Article Gastroenterology & Hepatology

The global burden of IBD: from 2015 to 2025

Gilaad G. Kaplan

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2015)

Review Pharmacology & Pharmacy

Dehydroepiandrosterone (DHEA): Hypes and Hopes

Krzysztof Rutkowski et al.

Article Endocrinology & Metabolism

Role of Androgen and Estrogen Receptors for the Action of Dehydroepiandrosterone (DHEA)

Cecilia Engdahl et al.

ENDOCRINOLOGY (2014)

Article Biochemistry & Molecular Biology

Large procyanidins prevent bile-acid-induced oxidant production and membrane-initiated ERK1/2, p38, and Akt activation in Caco-2 cells

Mathieu Da Silva et al.

FREE RADICAL BIOLOGY AND MEDICINE (2012)

Review Gastroenterology & Hepatology

Intestinal barrier function in health and gastrointestinal disease

M. Camilleri et al.

NEUROGASTROENTEROLOGY AND MOTILITY (2012)

Review Cell Biology

NF-kappa B in the regulation of epithelial homeostasis and inflammation

Andy Wullaert et al.

CELL RESEARCH (2011)

Article Medicine, Research & Experimental

PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and mice

Wei Qiu et al.

JOURNAL OF CLINICAL INVESTIGATION (2011)

Article Multidisciplinary Sciences

A role for mitochondria in NLRP3 inflammasome activation

Rongbin Zhou et al.

NATURE (2011)

Review Endocrinology & Metabolism

The G-protein-coupled estrogen receptor GPER in health and disease

Eric R. Prossnitz et al.

NATURE REVIEWS ENDOCRINOLOGY (2011)

Article Cell Biology

Asthma and Dehydroepiandrosterone (DHEA): Facts and Hypotheses

Alicja Kasperska-Zajac

INFLAMMATION (2010)

Article Biochemistry & Molecular Biology

Involvement of Interferon-γ in Bowel Disease Pathogenesis by Nitric Oxide Pathway: A Study in Algerian Patients

Hayet Rafa et al.

JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2010)

Article Cell Biology

GPR30/GPER-1 mediates rapid decreases in TLR4 expression on murine macrophages

Jennifer A. Rettew et al.

MOLECULAR AND CELLULAR ENDOCRINOLOGY (2010)

Article Gastroenterology & Hepatology

Evidence for tight junction protein disruption in intestinal mucosa of malignant obstructive jaundice patients

Na Wang et al.

SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY (2010)

Review Biochemistry & Molecular Biology

Cytokine regulation of tight junctions

Christopher T. Capaldo et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2009)

Review Biochemistry & Molecular Biology

Nrf2-induced antioxidant Protection: A Promising target to counteract ROS-mediated damage in neurodegenerative disease?

Helga E. de Vries et al.

FREE RADICAL BIOLOGY AND MEDICINE (2008)

Article Biochemistry & Molecular Biology

Dehydroepiandrosterone modulates antioxidant enzymes and Akt signaling in healthy Wistar rat hearts

Maria H. V. M. Jacob et al.

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2008)

Review Multidisciplinary Sciences

Immunity, inflammation, and allergy in the gut

TT MacDonald et al.

SCIENCE (2005)

Review Biochemistry & Molecular Biology

Role of reactive metabolites of oxygen and nitrogen in inflammatory bowel disease

KP Pavlick et al.

FREE RADICAL BIOLOGY AND MEDICINE (2002)

Article Biochemistry & Molecular Biology

Oxidative stress and eicosanoids in the kidneys of hyperglycemic rats treated with dehydroepiandrosterone

M Aragno et al.

FREE RADICAL BIOLOGY AND MEDICINE (2001)