期刊
FOOD AND BIOPRODUCTS PROCESSING
卷 128, 期 -, 页码 166-176出版社
ELSEVIER
DOI: 10.1016/j.fbp.2021.05.003
关键词
Antibacterial; Controlled-release; Docking; Electrospinning; Zein
资金
- Shiraz University Iran [9731763]
This study incorporated cuminaldehyde into zein solutions at different concentrations for electrospinning, resulting in optimized fibers with 20% cuminaldehyde. Through various chemical evaluations and experiments, the potential applications of cuminaldehyde-loaded zein fibers in food and therapeutic fields were confirmed and supported.
The zein solutions containing different concentrations of cuminaldehyde (5%, 10%, and 20%, w/w) were electrospun. The morphology and average diameter of fibers were evaluated by scanning electron microscopy and the optimized fiber (20% cuminaldehyde) was chosen. Proton nuclear magnetic resonance spectroscopy and encapsulation efficiency showed the presence and desirable content of loaded cuminaldehyde in cuminaldehyde-loaded zein fiber, respectively. Chemical evaluations using Fourier transform infrared spectroscopy, X-ray diffraction, and confocal Raman spectroscopy assigned the domination of helical domains, amorphousness, and acceptive distribution to the resultant fiber, respectively. Modeling of Z19 and Z22 as well as molecular docking confirmed the results of chemical evaluations. Furthermore, the enhanced onset thermostability of cuminaldehyde (from 80 to 99 degrees C) was observed after the incorporation into zein fiber. Finally, the diffusion controlledrelease of cuminaldehyde from a hydrophobic surface, its low-risk toxicity, and potent antibacterial activity of cuminaldehyde-loaded zein fiber against Staphylococcus aureus and Escherichia coli suggested its potentiality to be used in food and therapeutic applications. (c) 2021 Institution of Chemical Engineers. Published by Elsevier B.V. All rights reserved.
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