Ten new nortriterpenes from Euphorbia resinifera and their anti-tomato yellow leaf curl virus activities

Ten new nortriterpenes, euphorbiumrins A-J (1-10), together with three known analogues (11-13) were isolated from the latex of Euphorbia resinifera. Their structures were established on the basis of extensive spectroscopic analyses (IR, UV, HRESIMS, 1D and 2D NMR). Their inhibitions on tomato yellow leaf curl virus (TYLCV) were evaluated and compound 5 exhibited significant anti-TYLCV activity with an inhibition rate of 71.7% at concentration of 40 mu g/mL.

Automated summary

Ten new nortriterpenes, euphorbiumrins A-J, were isolated from the latex of Euphorbia resinifera, along with three known analogues. Compound 5 displayed significant anti-tomato yellow leaf curl virus (TYLCV) activity, with an inhibition rate of 71.7% at a concentration of 40 µg/mL.