相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。LC-MS bioanalysis of intact proteins and peptides
Lijuan Kang et al.
BIOMEDICAL CHROMATOGRAPHY (2020)
Proteolysis and Oxidation of Therapeutic Proteins After Intradermal or Subcutaneous Administration
Ninad Varkhede et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2020)
Physicochemical Stability of Monoclonal Antibodies: A Review
Yoann Le Basle et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2020)
An overview on dosage forms and formulation strategies for vaccines and antibodies oral delivery
Faten Madani et al.
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY (2020)
The Pharmaceutical Industry in 2019. An Analysis of FDA Drug Approvals from the Perspective of Molecules
Beatriz G. de la Torre et al.
MOLECULES (2020)
An atlas of the protein-coding genes in the human, pig, and mouse brain
Evelina Sjostedt et al.
SCIENCE (2020)
Review of recently used techniques and materials to improve the efficiency of orally administered proteins/peptides
Yousif H-E. Y. Ibrahim et al.
DARU-JOURNAL OF PHARMACEUTICAL SCIENCES (2020)
Oral delivery of protein-based therapeutics: Gastroprotective strategies, physiological barriers and in vitro permeability prediction
Leah Wright et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)
Approaches to improve intestinal and transmucosal absorption of peptide and protein drugs
Akira Yamamoto et al.
PHARMACOLOGY & THERAPEUTICS (2020)
Development of therapeutic antibodies for the treatment of diseases
Ruei-Min Lu et al.
JOURNAL OF BIOMEDICAL SCIENCE (2020)
Nanoparticles with surface features of dendritic oligopeptides as potential oral drug delivery systems
Yuli Bai et al.
JOURNAL OF MATERIALS CHEMISTRY B (2020)
iProt-Sub: a comprehensive package for accurately mapping and predicting protease-specific substrates and cleavage sites
Jiangning Song et al.
BRIEFINGS IN BIOINFORMATICS (2019)
Chemical Modification of the N Termini of Unprotected Peptides for Semisynthesis of Modified Proteins by Utilizing a Hydrophilic Protecting Group
Chaitra Chandrashekar et al.
CHEMISTRY-A EUROPEAN JOURNAL (2019)
A Comprehensive Review on Current Advances in Peptide Drug Development and Design
Andy Chi-Lung Lee et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Glucagon-Like Peptide-1 Receptor Agonists and Strategies To Improve Their Efficiency
Seyed Ebrahim Alavi et al.
MOLECULAR PHARMACEUTICS (2019)
Toxicity and immunogenicity concerns related to PEGylated-micelle carrier systems: a review
Kouichi Shiraishi et al.
SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS (2019)
Unnatural amino acids: production and biotechnological potential
Tanja Narancic et al.
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY (2019)
The Discovery and Development of Liraglutide and Semaglutide
Lotte Bjerre Knudsen et al.
FRONTIERS IN ENDOCRINOLOGY (2019)
Recent Advancements in Non-Invasive Formulations for Protein Drug Delivery
Rajiv Bajracharya et al.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2019)
A Chemical-Intervention Strategy To Circumvent Peptide Hydrolysis by D-Stereoselective Peptidases
Samantha J. Bann et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
The human secretome
Mathias Uhlen et al.
SCIENCE SIGNALING (2019)
The Mechanistic Impact of N-Glycosylation on Stability, Pharmacokinetics, and Immunogenicity of Therapeutic Proteins
Qun Zhou et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2019)
A genome-wide transcriptomic analysis of protein-coding genes in human blood cells
Mathias Uhlen et al.
SCIENCE (2019)
Mechanisms of gastrointestinal microflora on drug metabolism in clinical practice
Chaonan Sun et al.
SAUDI PHARMACEUTICAL JOURNAL (2019)
From Synthesis to Characterization of Site-Selective PEGylated Proteins
Lisandra Herrera Belen et al.
FRONTIERS IN PHARMACOLOGY (2019)
Therapeutic peptides: Historical perspectives, current development trends, and future directions
Jolene L. Lau et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2018)
Enzymatic asymmetric synthesis of chiral amino acids
Ya-Ping Xue et al.
CHEMICAL SOCIETY REVIEWS (2018)
Metabolism of Peptide Drugs and Strategies to Improve their Metabolic Stability
Jin-Feng Yao et al.
CURRENT DRUG METABOLISM (2018)
Fine-Tuning the Proteolytic Stability of Peptides with Fluorinated Amino Acids
Susanne Huhmann et al.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2018)
Proteolytic Cleavage-Mechanisms, Function, and Omic Approaches for a Near-Ubiquitous Posttranslational Modification
Theo Klein et al.
CHEMICAL REVIEWS (2018)
A subcellular map of the human proteome
Peter J. Thul et al.
SCIENCE (2017)
A pathology atlas of the human cancer transcriptome
Mathias Uhlen et al.
SCIENCE (2017)
The Oxytocin-vasopressin Pathway in the Context of Love and Fear
C. Sue Carter
FRONTIERS IN ENDOCRINOLOGY (2017)
Differential stability of therapeutic peptides with different proteolytic cleavage sites in blood, plasma and serum
Roland Boettger et al.
PLOS ONE (2017)
THPdb: Database of FDA-approved peptide and protein therapeutics
Salman Sadullah Usmani et al.
PLOS ONE (2017)
Nardilysin regulates inflammation, metaplasia, and tumors in murine stomach
Yuto Kimura et al.
SCIENTIFIC REPORTS (2017)
Position-dependent impact of hexafluoroleucine and trifluoroisoleucine on protease digestion
Susanne Huhmann et al.
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY (2017)
Human digestion-a processing perspective
Mike Boland
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE (2016)
A review on the strategies for oral delivery of proteins and peptides and their clinical perspectives
Abdul Muheem et al.
SAUDI PHARMACEUTICAL JOURNAL (2016)
PEGylation in anti-cancer therapy: An overview
Prajna Mishra et al.
ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2016)
Advances in Chemical Protein Modification
Omar Boutureira et al.
CHEMICAL REVIEWS (2015)
Toward Oral Delivery of Biopharmaceuticals: An Assessment of the Gastrointestinal Stability of 17 Peptide Drugs
Jie Wang et al.
MOLECULAR PHARMACEUTICS (2015)
Tissue-based map of the human proteome
Mathias Uhlen et al.
SCIENCE (2015)
LC-MS-based quantification of intact proteins: perspective for clinical and bioanalytical applications
Irene van den Broek et al.
BIOANALYSIS (2015)
Oxytocin and vasopressin: linking pituitary neuropeptides and their receptors to social neurocircuits
Danielle A. Baribeau et al.
FRONTIERS IN NEUROSCIENCE (2015)
Strategic Approaches to Optimizing Peptide ADME Properties
Li Di
AAPS JOURNAL (2015)
In Vitro Metabolic Stability of Exendin-4: Pharmacokinetics and Identification of Cleavage Products
Sha Liao et al.
PLOS ONE (2015)
Discussion about Several Potential Drawbacks of PEGylated Therapeutic Proteins
Fan Zhang et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2014)
PEGylation of lysine residues improves the proteolytic stability of fibronectin while retaining biological activity
Chen Zhang et al.
BIOTECHNOLOGY JOURNAL (2014)
Pharmacology, Physiology, and Mechanisms of Action of Dipeptidyl Peptidase-4 Inhibitors
Erin E. Mulvihill et al.
ENDOCRINE REVIEWS (2014)
Expression and activity of thimet oligopeptidase (TOP) are modified in the hippocampus of subjects with temporal lobe epilepsy (TLE)
Priscila Santos Rodrigues Simoes et al.
EPILEPSIA (2014)
Oral peptide and protein delivery: intestinal obstacles and commercial prospects
Alice L. Smart et al.
EXPERT OPINION ON DRUG DELIVERY (2014)
Peptides Containing β-Amino Acid Patterns: Challenges and Successes in Medicinal Chemistry
Chiara Cabrele et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
MEROPS: the database of proteolytic enzymes, their substrates and inhibitors
Neil D. Rawlings et al.
NUCLEIC ACIDS RESEARCH (2014)
Current challenges in peptide-based drug discovery
Laszlo Otvos et al.
FRONTIERS IN CHEMISTRY (2014)
N-Methylation of Peptides and Proteins: An Important Element for Modulating Biological Functions
Jayanta Chatterjee et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)
Improved Protease Stability of the Antimicrobial Peptide Pin2 Substituted with D-Amino Acids
G. Carmona et al.
PROTEIN JOURNAL (2013)
In Vitro Metabolism of the Glucagon-Like Peptide-1 (GLP-1)-Derived Metabolites GLP-1(9-36)amide and GLP-1(28-36)amide in Mouse and Human Hepatocytes
Raman Sharma et al.
DRUG METABOLISM AND DISPOSITION (2013)
Cysteine cathepsins: From structure, function and regulation to new frontiers
Vito Turk et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2012)
Probing protein stability and proteolytic resistance by loop scanning: A comprehensive mutational analysis
Shoeb Ahmad et al.
PROTEIN SCIENCE (2012)
Discovery and characterization of taspoglutide, a novel analogue of human glucagon-like peptide-1, engineered for sustained therapeutic activity in type 2 diabetes
J. Z. Dong et al.
DIABETES OBESITY & METABOLISM (2011)
An overview of once-weekly glucagon-like peptide-1 receptor agonists-available efficacy and safety data and perspectives for the future
S. Madsbad et al.
DIABETES OBESITY & METABOLISM (2011)
PK/PD modelling of comb-shaped PEGylated salmon calcitonin conjugates of differing molecular weights
Sinead M. Ryan et al.
JOURNAL OF CONTROLLED RELEASE (2011)
Lysosomal membrane permeabilization and cathepsin release is a Bax/Bak-dependent, amplifying event of apoptosis in fibroblasts and monocytes
C. Oberle et al.
CELL DEATH AND DIFFERENTIATION (2010)
Protein Chemical Modification on Endogenous Amino Acids
Emmanuel Basle et al.
CHEMISTRY & BIOLOGY (2010)
Liraglutide: the therapeutic promise from animal models
L. B. Knudsen
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE (2010)
Capillary electrophoresis with noncovalently bilayer-coated capillaries for stability study of allergenic proteins in simulated gastrointestinal fluids
Chang Zheng et al.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2010)
Cleavage of IgGs by proteases associated with invasive diseases An evasion tactic against host immunity?
Randall J. Brezski et al.
MABS (2010)
Expression of neutral endopeptidase activity during clinical and experimental acute lung injury
Soshi Hashimoto et al.
RESPIRATORY RESEARCH (2010)
Effects of Glycosylation on the Stability of Protein Pharmaceuticals
Ricardo J. Sola et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2009)
Angiotensin-(1-7) with Thioether Bridge: An Angiotensin-Converting Enzyme-Resistant, Potent Angiotensin-(1-7) Analog
Leon D. Kluskens et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2009)
Metabolic cleavage and translocation efficiency of selected cell penetrating peptides:: A comparative study with epithelial cell cultures
Christina Foerg et al.
AAPS JOURNAL (2008)
Cathepsin D is the main lysosomal enzyme involved in the degradation of α-synuclein and generation of its carboxy-terminally truncated species
Daniel Sevlever et al.
BIOCHEMISTRY (2008)
Granulocyte colony-stimulating factor: Molecular mechanisms of action during steady state and 'emergency' hematopoiesis
Athanasia D. Panopoulos et al.
CYTOKINE (2008)
Salmon calcitonin: a review of current and future therapeutic indications
C. H. Chesnut et al.
OSTEOPOROSIS INTERNATIONAL (2008)
Pancreatic enzyme pharmacotherapy
Marcus Ferrone et al.
PHARMACOTHERAPY (2007)
Human body fluid proteome analysis
Shen Hu et al.
PROTEOMICS (2006)
Glycosylation in the Fc domain of IgG increases resistance to proteolytic cleavage by papain
TS Raju et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
A human protein atlas for normal and cancer tissues based on antibody proteomics
M Uhlén et al.
MOLECULAR & CELLULAR PROTEOMICS (2005)
Basis for selectivity of cationic antimicrobial peptides for bacterial versus mammalian membranes
E Glukhov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Specificity of trypsin and chymotrypsin: Loop-motion-controlled dynamic correlation as a determinant
WZ Ma et al.
BIOPHYSICAL JOURNAL (2005)
Partial D-amino acid substitution:: Improved enzymatic stability and preserved Ab recognition of a MUC2 epitope peptide
R Tugyi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
The proteolytic stability of 'designed' beta-peptides containing alpha-peptide-bond mimics and of mixed alpha,beta-peptides: Application to the construction of MHC-binding peptides
DF Hook et al.
CHEMISTRY & BIODIVERSITY (2005)
Intracellular protein degradation: from a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting
A Ciechanover
CELL DEATH AND DIFFERENTIATION (2005)
Evolutionary families of peptidase inhibitors
ND Rawlings et al.
BIOCHEMICAL JOURNAL (2004)
The significance of carbohydrates on G-CSF: differential sensitivity of G-CSFs to human neutrophil elastase degradation
CRD Carter et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2004)
Pharmacological profiles of peptide drug candidates for the treatment of Alzheimer's disease
C Adessi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Potential utility of various protease inhibitors for improving the intestinal absorption of insulin in rats
H Liu et al.
JOURNAL OF PHARMACY AND PHARMACOLOGY (2003)
Furin at the cutting edge: From protein traffic to embryogenesis and disease
G Thomas
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
Increased proteolytic resistance of ribonuclease A by protein engineering
Y Markert et al.
PROTEIN ENGINEERING (2001)
分享论文
