期刊
EXPERIMENTAL EYE RESEARCH
卷 209, 期 -, 页码 -出版社
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.exer.2021.108670
关键词
Elasticity; Viscoelasticity; Adhesion energy; Intraocular pressures
资金
- National Natural Science Foundation of China [31800789, 11702184, 12072218, 11972243, 11872262]
A macro-indentation test was performed on intact cornea to analyze its behavior under physiological pressures, with the JKR model providing more accurate elastic modulus values than the Hertz model, due to its consideration of adhesion energy. This study indicates that the JKR model could be effectively used to obtain E values of intact cornea under physiological pressures.
In this study, a macro-indentation test on the submillimeter scale was performed to analyze the indentation behavior of an intact cornea under physiological pressures. The Hertz and Johnson-Kendall-Roberts (JKR) models were employed to solve the elastic modulus (E) of the intact cornea. The relevant detailed analysis showed that the JKR model, which accounted for the contribution from the adhesion energy, could be used to obtain the E values that were more than two-folds of those obtained from the Hertz model, which only considered the external force. Compared with the uniaxial tension test in vitro, unlike the elastic Hertz-model, the E values under physiological pressures that were obtained with the JKR model were between the lower and upper limits of corneal material. This phenomenon indicated that the JKR model could be used to obtain reasonably effective E values of an intact cornea under physiological pressures.
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