期刊
EVOLUTIONARY APPLICATIONS
卷 14, 期 11, 页码 2591-2602出版社
WILEY
DOI: 10.1111/eva.13294
关键词
environment; G x E; nematode; resistance; sheep; SNP; stress
资金
- ANR Institut Carnot Sante Animale programme (GEMANEMA project) [11 CARN 016-01]
Breeding resistant hosts is a sustainable strategy against drug-resistant parasites, although environmental variations and parasite species may impact the genetic potential of hosts.
Drug-resistant parasites threaten livestock production. Breeding more resistant hosts could be a sustainable control strategy. Environmental variation linked to animal management practices or to parasite species turnover across farms may however alter the expression of genetic potential. We created sheep lines with high or low resistance to Haemonchus contortus and achieved significant divergence on both phenotypic and genetic scales. We exposed both lines to chronic stress or to the infection by another parasite Trichostrongylus colubriformis, to test for genotype-by-environment and genotype-by-parasite species interactions respectively. Between-line divergence remained significant following chronic stress exposure although between-family variation was found. Significant genotype-by-parasite interaction was found although H. contortus-resistant lambs remained more resistant against T. colubriformis. Growth curves were not altered by the selection process although resistant lambs were lighter after the second round of divergence, before any infection took place. Breeding for resistance is a sustainable strategy but allowance needs to be made for environmental perturbations and worm species.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据