A case of blaNDM-1-positive Salmonella Kottbus, Denmark, November 2020

We present a case of carbapenemase-producing blaNDM-1-positive Salmonella Kottbus in an 82-year-old Danish man. The blaNDM-1 was also identified in Escherichia coli and Citrobacter freundii in the same patient on the same 43 kb IncN2 plasmid, suggesting in vivo inter-species plasmid transfer. A NCBI BLAST analysis of the plasmid (pAMA003584_NDM-1) identified 12 highly similar plasmids, all originating from east and south-east Asia. This case could be the first confirmed case of blaNDM-1-positive Salmonella not related to travel outside Europe.

Automated summary

An 82-year-old Danish man was infected with carbapenemase-producing blaNDM-1-positive Salmonella Kottbus. The blaNDM-1 gene was also found in Escherichia coli and Citrobacter freundii in the same patient, suggesting inter-species plasmid transfer in vivo. Analysis identified similar plasmids originating from East and Southeast Asia, indicating a possible origin for the infection.