期刊
EUROSURVEILLANCE
卷 26, 期 26, 页码 -出版社
EUR CENTRE DIS PREVENTION & CONTROL
DOI: 10.2807/1560-7917.ES.2021.26.26.2100557
关键词
-
资金
- Nehemia Rubin Excellence in Biomedical Research - The TELEM Program of Chaim Sheba Medical Center
The study found that healthcare workers vaccinated with Comirnaty showed reduced neutralising titres against the Gamma, Beta, and Delta variants, but the remaining neutralisation capacity may still be protective.
SARS-CoV-2 Delta (B.1.617.2) variant of concern (VOC) and other VOCs are spreading in Europe. Micro-neutralisation assays with sera obtained after Comirnaty (BNT162b2, BioNTech/Pfizer) vaccination in 36 healthcare workers (31 female) demonstrated significant fold change reduction in neutralising titres compared with the original virus: Gamma (P.1) 2.3, Beta (B.1.351) 10.4, Delta 2.1 and 2.6. The reduction of the Alpha (B.1.1.7) variant was not significant. Despite being lower, remaining neutralisation capacity conferred by Comirnaty against Delta and other VOCs is probably protective.
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