Construction of Si-Stereogenic Silanes through C-H Activation Approach

The asymmetric synthesis of Si-stereogenic silanes has attracted great attention due to the increasing values of Si-containing functional molecules in synthetic chemistry, medicinal chemistry, and material chemistry. Merging organosilicon chemistry with transition-metal-catalyzed C-H approach has led to rich sets of new reactions holding great synthetic values. This Minireview aims to summarize the advances in the construction of Si-stereogenic silanes through the transition-metal-catalyzed C-H activation approach.

Automated summary

This Minireview summarizes the recent advances in the construction of Si-stereogenic silanes through the transition-metal-catalyzed C-H activation approach, showcasing their significant synthetic value.