Asymmetric Organocatalysis Accelerated via Self-Assembled Minimal Structures

Self-assembling minimalistic peptides embedded with an organocatalytic moiety were designed. By controlling the formation of fibrils via external intervention, it was shown that the activation is accelerated when the organocatalyst is in its supramolecular state. The effect of the accelerated catalysis was demonstrated in a Michael benchmark reaction.

Automated summary

Self-assembling minimalistic peptides with an organocatalytic moiety were designed and controlled by external intervention to accelerate activation. The accelerated catalysis was demonstrated in a Michael benchmark reaction.