4.7 Article

Leu(27)IGF-II-induced hypertrophy in H9c2 cardiomyoblasts is ameliorated by saffron by regulation of calcineurin/NFAT and CaMKII delta signaling

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Environmental Sciences

Cardioprotective potential of amygdalin against angiotensin II induced cardiac hypertrophy, oxidative stress and inflammatory responses through modulation of Nrf2 and NF-κB activation

Yen-Lun Kung et al.

Summary: The study demonstrates that AMG can alleviate Ang II-induced cardiomyocyte enlargement, reduce the expression of hypertrophic and inflammatory markers, and increase oxidative stress related proteins. These findings highlight the cardio-protective role of AMG against Ang II-induced cardiomyopathies.

ENVIRONMENTAL TOXICOLOGY (2021)

Article Plant Sciences

Leech extract: A candidate cardioprotective against hypertension-induced cardiac hypertrophy and fibrosis

Chien-Hao Wang et al.

Summary: The study found that medicinal leech extract can significantly protect against hypertension-induced cardiac hypertrophy and fibrosis, reducing morbidity rates and potentially offering therapeutic value.

JOURNAL OF ETHNOPHARMACOLOGY (2021)

Article Environmental Sciences

Cardioprotective effects of transplanted adipose-derived stem cells under Ang II stress with Danggui administration augments cardiac function through upregulation of insulin-like growth factor 1 receptor in late-stage hypertension rats

Parthasarathi Barik et al.

Summary: The study showed that the combination of Danggui crude extract and stem cell therapy could enhance cardiac function, reduce hypertrophy in cardiomyocytes, and decrease the apoptosis rate in heart tissue of late-stage hypertensive rats.

ENVIRONMENTAL TOXICOLOGY (2021)

Review Food Science & Technology

Effects of phytochemicals on cellular signaling: reviewing their recent usage approaches

Dinh-Chuong Pham et al.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2020)

Article Biochemistry & Molecular Biology

Casticin inhibits human prostate cancer DU 145 cell migration and invasion via Ras/Akt/NF-κB signaling pathways

Chia-Chang Lin et al.

JOURNAL OF FOOD BIOCHEMISTRY (2019)

Article Pharmacology & Pharmacy

Safranal Alleviates Dextran Sulfate Sodium-Induced Colitis and Suppresses Macrophage-Mediated Inflammation

Peeraphong Lertnimitphun et al.

FRONTIERS IN PHARMACOLOGY (2019)

Review Medicine, Research & Experimental

Saffron; An updated review on biological properties with special focus on cardiovascular effects

Samad Ghaffari et al.

BIOMEDICINE & PHARMACOTHERAPY (2019)

Review Medicine, Research & Experimental

A comprehensive review of the pharmacological potential of Crocus sativus and its bioactive apocarotenoids

Syed Imran Bukhari et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

Review Endocrinology & Metabolism

The Relationship of Insulin-Like Growth Factor 2 to Fetal Growth and Adiposity

Rachel Kadakia et al.

HORMONE RESEARCH IN PAEDIATRICS (2016)

Review Chemistry, Medicinal

Antiinflammatory, Antioxidant, and Immunomodulatory Effects of Crocus sativus L. and its Main Constituents

Mohammad Hossein Boskabady et al.

PHYTOTHERAPY RESEARCH (2016)

Article Physiology

IGF-2R-Gαq signaling and cardiac hypertrophy in the low-birth-weight lamb

Kimberley C. W. Wang et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2015)

Review Pharmacology & Pharmacy

Herbal drugs against cardiovascular disease: traditional medicine and modern development

Lingjun Li et al.

DRUG DISCOVERY TODAY (2015)

Review Pharmacology & Pharmacy

Integrated mechanisms of CaMKII-dependent ventricular remodeling

Michael M. Kreusser et al.

FRONTIERS IN PHARMACOLOGY (2014)

Article Endocrinology & Metabolism

Alteration of cardiac glucose metabolism in association to low birth weight: Experimental evidence in lambs with left ventricular hypertrophy

Kimberley C. W. Wang et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2013)

Article Reproductive Biology

IGF-2R-Mediated Signaling Results in Hypertrophy of Cultured Cardiomyocytes from Fetal Sheep

Kimberley C. W. Wang et al.

BIOLOGY OF REPRODUCTION (2012)

Article Endocrinology & Metabolism

Insulin-like growth factor-II: new roles for an old actor

Stefano Cianfarani

Frontiers in Endocrinology (2012)

Article Cell Biology

The H9C2 cell line and primary neonatal cardiomyocyte cells show similar hypertrophic responses in vitro

Sarah J. Watkins et al.

IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL (2011)

Article Endocrinology & Metabolism

Leu27IGF2 plays an opposite role to IGF1 to induce H9c2 cardiomyoblast cell apoptosis via Gαq signaling

Ray-Jade Chen et al.

JOURNAL OF MOLECULAR ENDOCRINOLOGY (2009)

Article Biochemistry & Molecular Biology

Essential role of insulin and insulin-like growth factor 1 receptor signaling in cardiac development and function

Palle G. Laustsen et al.

MOLECULAR AND CELLULAR BIOLOGY (2007)

Review Cell Biology

Regulation of cardiac hypertrophy by intracellular signalling pathways

Joerg Heineke et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)

Article Medicine, Research & Experimental

CaM kinase II selectively signals to histone deacetylase 4 during cardiornyocyte hypertrophy

Johannes Backs et al.

JOURNAL OF CLINICAL INVESTIGATION (2006)

Article Cardiac & Cardiovascular Systems

Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy

BJ Wilkins et al.

CIRCULATION RESEARCH (2004)

Review Cardiac & Cardiovascular Systems

Calcineurin-NFAT signaling regulates the cardiac hypertrophic response in coordination with the MAPKs

JD Molkentin

CARDIOVASCULAR RESEARCH (2004)

Review Biochemistry & Molecular Biology

NFAT signaling: Choreographing the social lives of cells

GR Crabtree et al.

Review Pharmacology & Pharmacy

Ca2+/CaM-dependent kinases: From activation to function

SS Hook et al.

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2001)