期刊
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
卷 28, 期 45, 页码 64848-64857出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s11356-021-15473-2
关键词
Mumps; Air pollution; Distributed lag; O-3; Cumulative exposure
资金
- National Key R&D Program of China [2017YFC1502903]
- National Natural Science Foundation of China [22076129]
- Sichuan Key RD Project [2020YFS0055]
- Chengdu Major Technology Application and Demonstration Project [2020-YF09-00031-SN]
- Fundamental Research Funds for the Central Universities [YJ201765]
The study found that ozone exposure increases the risk of mumps infection, with the most significant impact occurring at a lag of 0-7 days, particularly on the 4th day.
In the present study, we aim to evaluate the delayed and cumulative effect of ozone (O-3) exposure on mumps in a megacity with high population density and high humidity. We took Chongqing, a megacity in Southwest China, as the research area and 2013-2017 as the research period. A total of 49,258 confirmed mumps cases were collected from 122 hospitals of Chongqing. We employed the distributed lag nonlinear models with quasi-Poisson link to investigate the relationship between prevalence of mumps and O-3 exposure after adjusting for the effects of meteorological conditions. The results show that the effect of O-3 exposure on mumps was mainly manifested in the lag of 0-7 days. The single-day ;lag effect was the most obvious on the 4th day, with the relative risk (RR) of mumps occurs of 1.006 (95% CI: 1.003-1.007) per 10 mu g/m(3) in the O-3 exposure. The cumulative RR within 7 days was 1.025 (95% CI: 1.013-1.038). Our results suggest that O-3 exposure can increase the risk of mumps infection, which fills the gap of relevant research in mountainous areas with high population density and high humidity.
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