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Molecularly imprinted polymers in toxicology: a literature survey for the last 5 years

期刊

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
卷 28, 期 27, 页码 35437-35471

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SPRINGER HEIDELBERG
DOI: 10.1007/s11356-021-14510-4

关键词

MIP; Toxicology; Sensor; Detection; Forensic; Pharmaceutic

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Toxicology, a science with roots in human history, studies the impact of toxic chemicals on human health, the environment, pharmaceuticals, and industry. Molecularly imprinted polymers show promise as tracking tools for detecting drugs and toxic substances and have potential applications in toxicology.
The science of toxicology dates back almost to the beginning of human history. Toxic chemicals, which are encountered in different forms, are always among the chemicals that should be investigated in criminal field, environmental application, pharmaceutic, and even industry, where many researches have been carried out studies for years. Almost all of not only drugs but also industrial dyes have toxic side and direct effects. Environmental micropollutants accumulate in the tissues of all living things, especially plants, and show short- or long-term toxic symptoms. Chemicals in forensic science can be known by detecting the effect they cause to the body with the similar mechanism. It is clear that the best tracking tool among analysis methods is molecularly printed polymer-based analytical setups. Different polymeric combinations of molecularly imprinted polymers allow further study on detection or extraction using chromatographic and spectroscopic instruments. In particular, methods used in forensic medicine can detect trace amounts of poison or biological residues on the scene. Molecularly imprinted polymers are still in their infancy and have many variables that need to be developed. In this review, we summarized how molecular imprinted polymers and toxicology intersect and what has been done about molecular imprinted polymers in toxicology by looking at the studies conducted in the last 5 years.

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