Polydopamine-modified MWCNTs-glassy Carbon Electrode, a Selective Electrochemical Morphine Sensor

An electrochemical sensor based on a glassy carbon electrode was prepared using f-MWCNTs and polydopamine. Several techniques were used to investigate the surface features. Voltammetric techniques were used to evaluate the electrocatalyst efficiency, and it was used for morphine determination using differential pulse voltammetry. Different parameters affecting the method's sensitivity and selectivity were optimized. The linear dynamic range was 0.075-75.0 mu M with a detection limit of 0.06 mu M morphine. Also, the method's selectivity was tested, which was proved to be satisfactory. Finally, the sensor was successfully used for morphine determination in human plasma and urine samples with acceptable results.

Automated summary

A electrochemical sensor based on glassy carbon electrode was prepared using f-MWCNTs and polydopamine for morphine determination. The sensor showed high sensitivity and good selectivity, with a linear dynamic range of 0.075-75.0 μM and a detection limit of 0.06 μM. The method was successfully applied to human plasma and urine samples for morphine determination.