期刊
EARLY INTERVENTION IN PSYCHIATRY
卷 16, 期 5, 页码 581-586出版社
WILEY
DOI: 10.1111/eip.13200
关键词
early intervention; first-episode schizophrenia; longitudinal invariance; negative symptoms; positive and negative syndrome scale
类别
资金
- Fundacao de Amparo a Pesquisa do Estado de Sao Paulo [FAPESP 2010/08968-6, 2014/07280-1, 2017/25016-8]
The study found that the PANSS negative unidimensional model is suitable for assessing the longitudinal change of negative symptoms in first-episode schizophrenia patients, while the two-correlated model did not show longitudinal invariance.
Aim Construct stability over time is required for reliable inference, but evidence regarding the longitudinal invariance of negative symptoms is still limited. Thus, we examined the longitudinal invariance of the negative dimension using the positive and negative syndrome scale (PANSS) in an antipsychotic-naive first-episode schizophrenia sample at baseline and after 10 weeks. Methods Our study was conducted at a specialized early intervention service. PANSS ratings were analysed for 138 patients, and two different models were specified and tested: a unidimensional and a two-correlated factor solution. Results The unidimensional model fulfilled criteria for longitudinal invariance, whilst the two-correlated did not. Conclusion Our study provides support for the PANSS negative unidimensional model use to evaluate negative symptoms' longitudinal change following first-episode schizophrenia.
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