期刊
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
卷 102, 期 1, 页码 -出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.diagmicrobio.2021.115540
关键词
SARS-CoV-2 variants; Diagnostic escape; B; 1; 1; 7; RT-PCR; Whole genome sequencing
Five SARS-CoV-2-positive samples showed N-gene drop-out in RT-PCR multiplex test, all harboring a deletion in the same region of the N gene. This highlights the importance of ongoing surveillance of viral evolution and diagnostic test performance.
Five SARS-CoV-2-positive samples showed N-gene drop-out with a RT-PCR multiplex test. WGS found all samples to harbor a deletion in the same region of the N gene, which is likely to impair the efficiency of amplification. This highlights the need for a continued surveillance of viral evolution and diagnostic test performance. (c) 2021 Published by Elsevier Inc.
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