SARS-CoV-2 infection and COVID-19 severity in individuals with prior seasonal coronavirus infection

We show that individuals with documented history of seasonal coronavirus have a similar SARS-CoV-2 infection rate and COVID-19 severity as those with no prior history of seasonal coronavirus. Our findings suggest prior infection with seasonal coronavirus does not provide immunity to subsequent infection with SARSCoV-2. (c) 2021 Elsevier Inc. All rights reserved.

Automated summary

The study shows that individuals with a history of seasonal coronavirus infection have similar rates of SARS-CoV-2 infection and severity of COVID-19 compared to those without such a history, indicating that prior infection with seasonal coronaviruses does not confer immunity to subsequent infection with SARS-CoV-2.