☆ 4.5 Review

Nails and COVID-19-A comprehensive review of clinical findings and treatment

DERMATOLOGIC THERAPY (2021)

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Editorial Material Infectious Diseases

Periungual desquamation in a Japanese adult recovering from severe COVID-19

Takato Nakamoto et al.

Summary: A 50-year-old Japanese male developed periungual desquamation in hands and feet during the recovery phase of severe COVID-19, caution may also be necessary in adults due to reported coronary lesions during the recovery phase of severe COVID-19 in children.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2021)

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Article Dermatology

Pediatric COVID toes and fingers

Merav Koschitzky et al.

Summary: The emergence of the COVID-19 pandemic has led to new cutaneous features in children, such as COVID toes resembling chilblains. Children with these lesions are less likely to show symptomatic COVID-19, and the chilblain-like lesions may reflect an immune response.

CLINICS IN DERMATOLOGY (2021)

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Letter Dermatology

Fluorescence of nails and hair on Wood's lamp examination in Covid pandemic; undefined effect of Favipiravir in humans

Melek Aslan Kayiran et al.

DERMATOLOGIC THERAPY (2021)

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Letter Dermatology

The Goldman-Fox syndrome: Treating and preventing green pseudomonas nails in the era of COVID-19

Robert A. Schwartz et al.

DERMATOLOGIC THERAPY (2021)

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Letter Dermatology

Transverse orange nail lesions following SARS-CoV-2 infection

Antonella Tammaro et al.

DERMATOLOGIC THERAPY (2021)

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Article Peripheral Vascular Disease

Nailfold capillaroscopy findings in patients with coronavirus disease 2019: Broadening the spectrum of COVID-19 microvascular involvement

Gerlando Natalello et al.

Summary: COVID-19 patients exhibit microvascular abnormalities in NVC examination. Currently ill and recovered subjects show different distribution of elementary capillaroscopic alterations, resembling acute and post-acute microvascular damage. Further studies are needed to evaluate the clinical significance of NVC in COVID-19.

MICROVASCULAR RESEARCH (2021)

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Review Allergy

Cutaneous Manifestations Related to COVID-19 Immune Dysregulation in the Pediatric Age Group

Desiree Larenas-Linnemann et al.

Summary: The skin manifestations associated with COVID-19 in the pediatric age group are diverse, including purpuric, morbilliform/maculopapular, erythema multiforme, and urticarial. These skin features may be the result of various complex mechanisms such as direct virus-induced skin damage, vasculitis-like reactions, or systemic inflammatory reactions.

CURRENT ALLERGY AND ASTHMA REPORTS (2021)

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Article Medicine, General & Internal

Characteristics and Outcomes of US Children and Adolescents With Multisystem Inflammatory Syndrome in Children (MIS-C) Compared With Severe Acute COVID-19

Leora R. Feldstein et al.

Summary: Comparing the clinical characteristics and outcomes of patients with MIS-C and COVID-19 can help distinguish between the two conditions and improve health outcomes. Patterns of clinical presentation and organ system involvement were identified in this case series, providing valuable information for differentiation of MIS-C and COVID-19.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

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Editorial Material Public, Environmental & Occupational Health

'Blue toes' following vaccination with the Pfizer BNT162b2 mRNA COVID-19 vaccine

Benjamin Davido et al.

JOURNAL OF TRAVEL MEDICINE (2021)

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Article Pediatrics

Factors linked to severe outcomes in multisystem inflammatory syndrome in children (MIS-C) in the USA a retrospective surveillance study

Joseph Y. Abrams et al.

Summary: Factors such as age, race, clinical symptoms, and laboratory markers were found to be associated with severe outcomes in patients with MIS-C. These findings highlight the importance of early recognition and prompt management for patients with MIS-C.

LANCET CHILD & ADOLESCENT HEALTH (2021)

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Letter Dermatology

Beau-Lines of the fingernails in association with pediatric SARS-CoV-2 infections

Gerhard K. Wolf et al.

JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT (2021)

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Review Dermatology

Chilblain-Like Lesions (CLL) Associated With COVID-19 (COVID Toes): A Systematic Review

Nadia Kashetsky et al.

Summary: This study summarized reports of chilblain-like lesions (CLL) coinciding with SARS-CoV-2 infection from 31 papers, representing 813 cases. Data showed an equal gender distribution among CLL patients with a mean age of 21 years, mainly presenting as erythematous to violaceous acral macules and plaques, with 15% testing positive for SARS-CoV-2.

JOURNAL OF CUTANEOUS MEDICINE AND SURGERY (2021)

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Letter Dermatology

Improving cultural competency and practicing cultural humility in dermatologic training: Skin of color education and board certification

Trisha Kaundinya et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2021)

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Letter Dermatology

Nail changes as manifestation of systemic disease in COVID-19 infection

S. S. Ocampo-Garza et al.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2021)

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Letter Dermatology

Heterogeneous red-white discoloration of the nail bed and distal onycholysis in a patient with COVID-19

B. Demir et al.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2021)

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Article Immunology

ACRAL GANGRENE: UGLY COUSIN OF COVID TOES IN MULTISYSTEM INFLAMMATORY SYNDROME IN CHILDREN ASSOCIATED WITH SARS-COV-2?

Himanshi Chaudhary et al.

Summary: Dermatologic manifestations have been reported in children with multisystem inflammatory syndrome associated with SARS-CoV-2 infection, with some cases developing acral gangrene. However, both patients in this report responded well to therapy and recovered during follow-up.

PEDIATRIC INFECTIOUS DISEASE JOURNAL (2021)

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Letter Dermatology

Yellow-white fluorescence on the nails: A novel finding of Favipiravir used for the treatment of COVID-19

Duygu Gulseren et al.

JOURNAL OF COSMETIC DERMATOLOGY (2021)

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Review Infectious Diseases

Coronavirus disease (COVID-19) pandemic: an overview of systematic reviews

Israel Junior Borges do Nascimento et al.

Summary: This study analyzed 18 systematic reviews published early in the COVID-19 pandemic, finding critically low confidence in all review results. Symptoms of COVID-19 included fever, cough, dyspnea, muscle fatigue, sore throat, headache, and gastrointestinal complaints. Severe symptoms were more common in men, and abnormal biochemical markers were associated with severe disease.

BMC INFECTIOUS DISEASES (2021)

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Editorial Material Rheumatology

A Case of Chilblains-like Lesions Post SARS-CoV-2 Vaccine?

Alexa Simon Meara et al.

JOURNAL OF RHEUMATOLOGY (2021)

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Letter Dermatology

A review of nail findings associated with COVID-19 infection

E. Hadeler et al.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2021)

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Letter Dermatology

Chilblain-like lesions after BNT162b2 mRNA COVID-19 vaccine: a case report suggesting that 'COVID toes' are due to the immune reaction to SARS-CoV-2

C. Lesort et al.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2021)

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Article Medicine, General & Internal

Bilateral Chilblain-like Lesions of the Toes Characterized by Microvascular Remodeling in Adolescents During the COVID-19 Pandemic

Valentina Discepolo et al.

Summary: This study investigated the association of chilblain-like lesions with SARS-CoV-2 infection in 17 adolescents during the COVID-19 pandemic in Italy. The results did not support their association with SARS-CoV-2 infection, as the virus was excluded by molecular and serologic testing. Chilblain-like lesions in otherwise healthy adolescents were characterized by microvascular remodeling with perivascular lymphocytic infiltrate but no signs of vasculitis.

JAMA NETWORK OPEN (2021)

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Letter Dermatology

Chloronychia in Healthcare Workers in COVID-19 Times

Anca E. Chiriac et al.

SKIN APPENDAGE DISORDERS (2021)

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Review Hematology

COVID-19-associated coagulopathy and disseminated intravascular coagulation

Hidesaku Asakura et al.

Summary: The pathology of COVID-19 is exacerbated by thrombosis, DIC, and cytokine storms. D-dimer levels are commonly elevated in COVID-19, but relying solely on this marker has limitations. Treatment should be individualized based on disease severity and stage, with potential for combination therapy using heparin and nafamostat in the future. Further research is needed on fibrinolytic therapy and adsorption therapy.

INTERNATIONAL JOURNAL OF HEMATOLOGY (2021)

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Article Dermatology

Retrospective Case Series on Risk Factors, Diagnosis and Treatment of Pseudomonas aeruginosa Nail Infections

Solomon Geizhals et al.

AMERICAN JOURNAL OF CLINICAL DERMATOLOGY (2020)

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Article Medicine, General & Internal

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

Chaolin Huang et al.

LANCET (2020)

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Article Dermatology

Classification of the cutaneous manifestations of COVID-19: a rapid prospective nationwide consensus study in Spain with 375 cases

C. Galvan Casas et al.

BRITISH JOURNAL OF DERMATOLOGY (2020)

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Review Dermatology

Cutaneous signs in COVID-19 patients: A review

Uwe Wollina et al.

DERMATOLOGIC THERAPY (2020)

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Letter Dermatology

Chilblains is a common cutaneous finding during the COVID-19 pandemic: A retrospective nationwide study from France

Adele de Masson et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2020)

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Letter Dermatology

Transverse leukonychia (Mees' lines) nail alterations in aCOVID-19 patient

Diego Fernandez-Nieto et al.

DERMATOLOGIC THERAPY (2020)

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Letter Dermatology

Lack of association between chilblains outbreak and severe acute respiratory syndrome coronavirus 2: Histologic and serologic findings from a new immunoassay

Vivien Hebert et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2020)

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Article Dermatology

Chilblain-like acral lesions during the COVID-19 pandemic (COVID): Histologic, immunofluorescence, and immunohistochemical study of 17 cases

Jean Kanitakis et al.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY (2020)

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Letter Dermatology

The red half-moon nail sign: a novel manifestation of coronavirus infection

I. Neri et al.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2020)

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Editorial Material Medicine, General & Internal

Beau lines associated with COVID-19

Saud Alobaida et al.

CANADIAN MEDICAL ASSOCIATION JOURNAL (2020)

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Letter Dermatology

Onychomadesis following COVID-19 infection: Is there a relationship?

Nilgun Senturk et al.

DERMATOLOGIC THERAPY (2020)

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Article Dermatology

Prospective study on hand dermatitis in nurses and doctors duringCOVID-19 pandemic and its improvement by use of adopted recommendations of the European Academy of Dermatology and Venereology Task Force on Contact Dermatitis

Pavel V. Chernyshov et al.

DERMATOLOGIC THERAPY (2020)

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Article Dermatology

High prevalence of cryofibrinogenemia in patients with chilblains during the COVID-19 outbreak

Cristina Gomez-Fernandez et al.

INTERNATIONAL JOURNAL OF DERMATOLOGY (2020)

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Letter Dermatology

COVID-19 and nail manifestation: be on the lookout for the red half-moon nail sign

Silvia Mendez-Flores et al.

INTERNATIONAL JOURNAL OF DERMATOLOGY (2020)

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Editorial Material Medicine, General & Internal

Beau's Lines and Leukonychia in a COVID-19 Patient

Satoshi Ide et al.

INTERNAL MEDICINE (2020)

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Article Rheumatology

Familial chilblain lupus due to a gain-of-function mutation in STING

Nadja Konig et al.

ANNALS OF THE RHEUMATIC DISEASES (2017)

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Article Dermatology

Clinical and dermoscopic clues to differentiate pigmented nail bands: an International Dermoscopy Society study

E. Benati et al.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2017)

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Review Chemistry, Medicinal

Onychomadesis associated with chemotherapy: case report and mini literature review

Ang Li et al.

DRUG DESIGN DEVELOPMENT AND THERAPY (2017)

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Review Rheumatology

Cryofibrinogenemia

Martin Michaud et al.

JCR-JOURNAL OF CLINICAL RHEUMATOLOGY (2013)

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