Synthetic and Biological Attributes of Pyrimidine Derivatives: A Recent Update

Nitrogen-containing heterocycles attract the attention of chemists due to their multifarious activities. Amongst all, pyrimidine plays a central role and exhibits a broad spectrum of biological activities. Literature is replete with various aspects of synthetic development in the chemistry of pyrimidine for a wide array of appli-cations. It aroused our interest to compile various novel and efficient synthetic approaches towards the synthe-sis of pyrimidine and its derivatives. Pyrimidine derivatives are broadly useful as therapeutic agents, owing to their high degree of structural diversity. They have been recorded to possess a diverse range of therapeutic ac-tivities viz. anticancer, anti-inflammatory, anti-HIV etc.

Automated summary

Nitrogen-containing heterocycles, particularly pyrimidine, have drawn significant attention from chemists due to their diverse biological activities and potential therapeutic applications. Pyrimidine derivatives, with their high degree of structural diversity, exhibit a wide range of therapeutic activities such as anticancer, anti-inflammatory, and anti-HIV properties.