期刊
CURRENT ORGANIC CHEMISTRY
卷 25, 期 22, 页码 2765-2790出版社
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1385272825666210812102416
关键词
Synthesis; dicarbonyl compounds; diketones; nitrogen; heterocycles; six-membered
Various diketones and dicarbonyl compounds play significant roles in the synthesis of core heterocyclic compounds and also act as chelating ligands. Organic chemists have focused on the synthesis of nitrogen-containing heterocyclic compounds.
Various diketones such as 1,2-diketones, 1,3-diketones, 1,4-diketones, beta- diketones and dicarbonyl compounds are used in the synthesis of core heterocyclic compounds such as pyrazoles, isoxazoles, triazoles and quinolones. They play an important role in synthetic organic chemistry. The diketones and dicarbonyl compounds also act as chelating ligands for the lanthanides and a large number of transition metals in material chemistry. 50% of drugs contain nitrogen heterocyclic compounds, so organic chemists have made efforts for the synthesis of nitrogen -containing heterocyclic compounds. This review article has compiled different methodologies for the synthesis of five-and six-membered nitrogen containing heterocyclic compounds.
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