期刊
CURRENT OPINION IN MICROBIOLOGY
卷 61, 期 -, 页码 67-72出版社
CURRENT BIOLOGY LTD
DOI: 10.1016/j.mib.2021.03.004
关键词
-
类别
资金
- N.I.H. [R15GM140433]
- Robert C. and Sandra Connor Endowed Faculty Fellowship
- CEMB RA fund from University of Arkansas
This review summarizes useful tools based on the genetic code expansion technique for tackling challenges in studying and engineering BMCs. By introducing various noncanonical amino acids, genetic code expansion provides powerful tools for protein research and engineering.
Bacterial microcompartments (BMCs) with selectively permeable shells and encapsulated enzyme cores are well suited candidates for nano-bioreactors because of their advantages of enhancing pathway flux and protection against toxic products. To better study and engineer protein-based BMCs, a series of protein chemistry approaches are adopted. As one of the most advanced techniques, genetic code expansion can introduce various noncanonical amino acids (ncAAs) with diverse functional groups into target proteins, thus providing powerful tools for protein studies and engineering. This review summarizes and proposes useful tools based on current development of the genetic code expansion technique towards challenges in BMC studies and engineering.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据