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HEPATOLOGY (2021)
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CARCINOGENESIS (2020)
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DEVELOPMENTAL CELL (2020)
Inhibition of DCLK1 down-regulates PD-L1 expression through Hippo pathway in human pancreatic cancer
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Cancer Stem Cell Marker DCLK1 Correlates with Tumorigenic Immune Infiltrates in the Colon and Gastric Adenocarcinoma Microenvironments
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DCLK1 Regulates Tumor Stemness and Cisplatin Resistance in Non-small Cell Lung Cancer via ABCD-Member-4
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MOLECULAR THERAPY-ONCOLYTICS (2020)
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NATURE CHEMICAL BIOLOGY (2020)
PD-L1 expression levels on tumor cells affect their immunosuppressive activity
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ONCOLOGY LETTERS (2019)
Overexpression of DCLK1-AL Increases Tumor Cell Invasion, Drug Resistance, and KRAS Activation and Can Be Targeted to Inhibit Tumorigenesis in Pancreatic Cancer
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JOURNAL OF ONCOLOGY (2019)
Genomics and Targeted Therapies in Gastroesophageal Adenocarcinoma
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CANCER DISCOVERY (2019)
Inhibition of LEF1-Mediated DCLK1 by Niclosamide Attenuates Colorectal Cancer Stemness
So-Yeon Park et al.
CLINICAL CANCER RESEARCH (2019)
Identification of type I and type II inhibitors of c-Yes kinase using in silico and experimental techniques
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JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2018)
miR-424-5p regulates cell proliferation, migration and invasion by targeting doublecortin-like kinase 1 in basal-like breast cancer
Jianling Wang et al.
BIOMEDICINE & PHARMACOTHERAPY (2018)
DCLK1 promotes epithelial-mesenchymal transition via the PI3K/Akt/NF-κB pathway in colorectal cancer
Weiying Liu et al.
INTERNATIONAL JOURNAL OF CANCER (2018)
Osimertinib in Untreated EGFR-Mutated Advanced Non-Small-Cell Lung Cancer
J. -C. Soria et al.
NEW ENGLAND JOURNAL OF MEDICINE (2018)
Doublecortin-Like Kinase 1 (DCLK1) Regulates B Cell-Specific Moloney Murine Leukemia Virus Insertion Site 1 (Bmi-1) and is Associated with Metastasis and Prognosis in Pancreatic Cancer
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CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018)
Dclk1, a tumor stem cell marker, regulates pro-survival signaling and self-renewal of intestinal tumor cells
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MOLECULAR CANCER (2017)
FOXD3 Regulates CSC Marker, DCLK1-S, and Invasive Potential: Prognostic Implications in Colon Cancer
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MOLECULAR CANCER RESEARCH (2017)
Revisiting epithelial-mesenchymal transition in cancer metastasis: the connection between epithelial plasticity and stemness
Tsai-Tsen Liao et al.
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Nerve Growth Factor Promotes Gastric Tumorigenesis through Aberrant Cholinergic Signaling
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CANCER CELL (2017)
Dclk1 Defines Quiescent Pancreatic Progenitors that Promote Injury-Induced Regeneration and Tumorigenesis
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CELL STEM CELL (2016)
The bad seed: Cancer stem cells in tumor development and resistance
Elle Koren et al.
DRUG RESISTANCE UPDATES (2016)
Microtubule-binding protein doublecortin-like kinase 1 (DCLK1) guides kinesin-3-mediated cargo transport to dendrites
Joanna Lipka et al.
EMBO JOURNAL (2016)
miR-137 Regulates the Tumorigenicity of Colon Cancer Stem Cells through the Inhibition of DCLK1
Masazumi Sakaguchi et al.
MOLECULAR CANCER RESEARCH (2016)
Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut
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SCIENCE (2016)
Biochemical and Structural Insights into Doublecortin-like Kinase Domain 1
Onisha Patel et al.
STRUCTURE (2016)
Dynamic Expansion of Gastric Mucosal Doublecortin-Like Kinase 1-Expressing Cells in Response to Parietal Cell Loss Is Regulated by Gastrin
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AMERICAN JOURNAL OF PATHOLOGY (2015)
Upregulation of circulating cancer stem cell marker, DCLK1 but not Lgr5, in chemoradiotherapy-treated colorectal cancer patients
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TUMOR BIOLOGY (2015)
DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinoma
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ONCOTARGET (2015)
Epigenetic changes and alternate promoter usage by human colon cancers for expressing DCLK1-isoforms: Clinical Implications
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SCIENTIFIC REPORTS (2015)
DCLK1 Is Detectable in Plasma of Patients with Barrett's Esophagus and Esophageal Adenocarcinoma
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DIGESTIVE DISEASES AND SCIENCES (2015)
The novel colorectal cancer biomarkers CDO1, ZSCAN18 and ZNF331 are frequently methylated across gastrointestinal cancers
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INTERNATIONAL JOURNAL OF CANCER (2015)
Nuclear translocation of doublecortin-like protein kinase and phosphorylation of a transcription factor JDP2
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism
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CANCER LETTERS (2014)
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CANCER RESEARCH (2014)
The recently suggested intestinal cancer stem cell marker DCLK1 is an epigenetic biomarker for colorectal cancer
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DCLK1 Marks a Morphologically Distinct Subpopulation of Cells With Stem Cell Properties in Preinvasive Pancreatic Cancer
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GASTROENTEROLOGY (2014)
Long-lived intestinal tuft cells serve as colon cancer-initiating cells
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JOURNAL OF CLINICAL INVESTIGATION (2014)
Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1
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MOLECULAR CANCER (2014)
Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer
Kai Wang et al.
NATURE GENETICS (2014)
Dclk1 facilitates intestinal tumor growth via enhancing pluripotency and epithelial mesenchymal transition
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ONCOTARGET (2014)
DNA methyltransferases: a novel target for prevention and therapy
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FRONTIERS IN ONCOLOGY (2014)
Dclk1 distinguishes between tumor and normal stem cells in the intestine
Yuki Nakanishi et al.
NATURE GENETICS (2013)
Molecular Basis for Specific Regulation of Neuronal Kinesin-3 Motors by Doublecortin Family Proteins
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MOLECULAR CELL (2012)
DCLK1 Variants Are Associated across Schizophrenia and Attention Deficit/Hyperactivity Disorder
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PLOS ONE (2012)
DCLK I immunoreactivity in colorectal neoplasia
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CLINICAL AND EXPERIMENTAL GASTROENTEROLOGY (2012)
DCAMKL-1 Regulates Epithelial-Mesenchymal Transition in Human Pancreatic Cells through a miR-200a-Dependent Mechanism
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CANCER RESEARCH (2011)
Gastric tuft cells express DCLK1 and are expanded in hyperplasia
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JOURNAL OF VIROLOGY (2011)
Characterization of a selective inhibitor of the Parkinson's disease kinase LRRK2
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NATURE CHEMICAL BIOLOGY (2011)
Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism
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JOURNAL OF NANOBIOTECHNOLOGY (2011)
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Identification of a novel putative pancreatic stem/progenitor cell marker DCAMKL-1 in normal mouse pancreas
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AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2010)
Pharmacological Inhibition of BMK1 Suppresses Tumor Growth through Promyelocytic Leukemia Protein
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CANCER CELL (2010)
Identification of an endogenous substrate of zebrafish doublecortin-like protein kinase using a highly active truncation mutant*
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JOURNAL OF BIOCHEMISTRY (2010)
Selective Blockade of DCAMKL-1 Results in Tumor Growth Arrest by a Let-7a MicroRNA-Dependent Mechanism
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GASTROENTEROLOGY (2009)
DCAMKL-1 Expression Identifies Tuft Cells Rather Than Stem Cells in the Adult Mouse Intestinal Epithelium
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GASTROENTEROLOGY (2009)
Gefitinib or Carboplatin-Paclitaxel in Pulmonary Adenocarcinoma.
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NEW ENGLAND JOURNAL OF MEDICINE (2009)
Variants in Doublecortin- and Calmodulin Kinase Like 1, a Gene Up-Regulated by BDNF, Are Associated with Memory and General Cognitive Abilities
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PLOS ONE (2009)
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NATURE REVIEWS CANCER (2009)
CASK functions as a Mg2+-independent neurexin kinase
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CELL (2008)
Identification of a novel putative gastrointestinal stem cell and adenoma stem cell marker, doublecortin and CaM kinase-like-1, following radiation injury and in adenomatous polyposis coli/multiple intestinal neoplasia mice
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STEM CELLS (2008)
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DEVELOPMENTAL NEUROSCIENCE (2008)
Genetic interactions between doublecortin and doublecortin-like kinase in neuronal migration and axon outgrowth
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NEURON (2006)
doublecortin-like kinase functions with doublecortin to mediate fiber tract decussation and neuronal migration
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NEURON (2006)
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NEURON (2006)
Structure of the autoinhibited kinase domain of CaMKII and SAXS analysis of the holoenzyme
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CELL (2005)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
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