期刊
CURRENT BIOLOGY
卷 31, 期 14, 页码 R918-R929出版社
CELL PRESS
DOI: 10.1016/j.cub.2021.06.049
关键词
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资金
- Natural Sciences and Engineering Research Council of Canada [RGPIN-2016-03711, RGPIN-2013-217636]
- Canada 150 Research Chair
- Public Health Agency of Canada
- CIHR 2019 Novel Coronavirus (COVID-19) rapid research program
- M.G. DeGroote Institute for Infectious Disease Research at McMaster University
After a year into the COVID-19 pandemic, attention has shifted to the emergence and spread of variants of concern (VOCs) of SARS-CoV-2. These variants have shown detrimental effects on virus transmission and severity, prompting global efforts to understand their impact on disease control and public health interventions. Efforts are being made to explore the evolutionary processes involved in the emergence of new variants and to minimize their impact on the ongoing pandemic.
One year into the global COVID-19 pandemic, the focus of attention has shifted to the emergence and spread of SARS-CoV-2 variants of concern (VOCs). After nearly a year of the pandemic with little evolutionary change affecting human health, several variants have now been shown to have substantial detrimental effects on transmission and severity of the virus. Public health officials, medical practitioners, scientists, and the broader community have since been scrambling to understand what these variants mean for diagnosis, treatment, and the control of the pandemic through nonpharmaceutical interventions and vaccines. Here we explore the evolutionary processes that are involved in the emergence of new variants, what we can expect in terms of the future emergence of VOCs, and what we can do to minimise their impact.
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