期刊
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
卷 62, 期 30, 页码 8467-8496出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/10408398.2021.1929058
关键词
Nanotechnology; garlic bioactive compounds; bioavailability; bioactivity; applications
资金
- National Natural Science Foundation of China [31972000, 31801559]
- Major Scientific and Technological Innovation Projects of Key R&D Program of Shandong Province [2019JZZY020607]
This review highlights the main bioactive compounds and important biological functions of garlic, especially its anticancer effects. It also discusses the use of nanotechnology to improve the stability and solubility of garlic components, aiming to provide guidelines for enhancing the absorption and efficacy of garlic products. The application of nanotechnology in improving the bioavailability and targeting of garlic compounds shows promising potential for treating human health issues, including cancer.
This review highlights main bioactive compounds and important biological functions especially anticancer effects of the garlic. In addition, we review current literature on the stability and bioavailability of garlic components. Finally, this review aims to provide a potential strategy for using nanotechnology to increase the stability and solubility of garlic components, providing guidelines for the qualities of garlic products to improve their absorption and prevent their early degradation, and extend their circulation time in the body. The application of nanotechnology to improve the bioavailability and targeting of garlic compounds are expected to provide a theoretical basis for the functional components of garlic to treat human health. We review the improvement of bioavailability and bioactivity of garlic bioactive compounds via nanotechnology, which could promisingly overcome the limitations of conventional garlic products, and would be used to prevent and treat cancer and other diseases in the near future.
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