Catalytic function, mechanism, and application of plant acyltransferases

Acyltransferases (ATs) are important tailoring enzymes that contribute to the diversity of natural products. They catalyze the transfer of acyl groups to the skeleton, which improves the lipid solubility, stability, and pharmacological activity of natural compounds. In recent years, a number of ATs have been isolated from plants. In this review, we have summarized 141 biochemically characterized ATs during the period July 1997 to October 2020, including their function, heterologous expression systems, and catalytic mechanisms. Their catalytic performance and application potential has been further discussed.

Automated summary

Acyltransferases (ATs) are important tailoring enzymes that enhance the diversity and biological activity of natural products. This review summarizes 141 biochemically characterized ATs, discussing their catalytic properties and potential applications.