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Applications of Microfluidic Devices in the Diagnosis and Treatment of Cancer: A Review Study

期刊

CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
卷 52, 期 8, 页码 1863-1877

出版社

TAYLOR & FRANCIS INC
DOI: 10.1080/10408347.2021.1922870

关键词

Cancer; diagnosis; drug delivery; gene delivery; microfluidics; radiotherapy

资金

  1. Department of Immunology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran [85670]

向作者/读者索取更多资源

Microfluidic technology plays an important role in the cancer field by handling small volumes of materials for diagnosis and treatment, offering advantages such as high throughput, high sensitivity, minimal material use, and low cost. Through the use of microfluidics, various cancer treatments can be implemented and studied effectively.
Many cancer-related deaths are reported annually due to a lack of appropriate diagnosis and treatment strategies. Microfluidic technology, as new creativity has a great impact on automation and miniaturization via handling a small volume of materials and samples (in microliter to femtoliter range) to set up the system. Microfluidic devices not only detect various cancer-diagnostic factors from biological fluids but also can produce proper nanoparticles for drug delivery. With the contribution of microfluidics; multiple treatments for cancer such as chemotherapy, radiation therapy, and gene delivery can be implemented and studied. Hence, Microfluidics can be worth for the cancer field because of its high Throughput, high sensitivity, less material use, and low expense. In this review study, we intend to look at positive microfluidics prospects, features, benefits, and clinical applications.

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